4.6 Article

Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth

Shuaishuai Ni et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Structural insights into actin filament recognition by commonly used cellular actin markers

Archana Kumari et al.

EMBO JOURNAL (2020)

Article Genetics & Heredity

Heterozygous missense variants of SPTBN2 are a frequent cause of congenital cerebellar ataxia

Francesco Nicita et al.

CLINICAL GENETICS (2019)

Article Biochemistry & Molecular Biology

Noncompetitive inhibitors of TNFR1 probe conformational activation states

Chih Hung Lo et al.

SCIENCE SIGNALING (2019)

Article Biochemistry & Molecular Biology

High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function

Piyali Guhathakurta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Chemistry, Analytical

Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening

Tory M. Schaaf et al.

BIOSENSORS-BASEL (2018)

Article Biochemical Research Methods

Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells

Tory M. Schaaf et al.

SLAS DISCOVERY (2017)

Article Multidisciplinary Sciences

β-III-spectrin spinocerebellar ataxia type 5 mutation reveals a dominant cytoskeletal mechanism that underlies dendritic arborization

Adam W. Avery et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation

Adam W. Avery et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding

Adam W. Avery et al.

SCIENTIFIC REPORTS (2016)

Article Chemistry, Medicinal

An Aggregation Advisor for Ligand Discovery

John J. Irwin et al.

JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Biochemical Research Methods

Discovery of Enzyme Modulators via High-Throughput Time-Resolved FRET in Living Cells

Simon J. Gruber et al.

JOURNAL OF BIOMOLECULAR SCREENING (2014)

Article Biotechnology & Applied Microbiology

High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

Volker Jaeger et al.

BMC BIOTECHNOLOGY (2013)

Article Genetics & Heredity

Mutations in the N-terminal Actin-Binding Domain of Filamin C Cause a Distal Myopathy

Rachael M. Duff et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Review Pharmacology & Pharmacy

Principles of early drug discovery

J. P. Hughes et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Editorial Material Biochemical Research Methods

Forster distances for fluorescence resonant energy transfer between mCherry and other visible fluorescent proteins

Nina Akrap et al.

ANALYTICAL BIOCHEMISTRY (2010)

Article Chemistry, Medicinal

Colloid Formation by Drugs in Simulated Intestinal Fluid

Allison K. Doak et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Chemistry, Medicinal

Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors

Rafaela S. Ferreira et al.

JOURNAL OF MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Myosin Isoform Determines the Conformational Dynamics and Cooperativity of Actin Filaments in the Strongly Bound Actomyosin Complex

Ewa Prochniewicz et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Article Multidisciplinary Sciences

Disease-causing missense mutations in actin binding domain 1 of dystrophin induce thermodynamic instability and protein aggregation

Davin M. Henderson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Cardiotoxicity of calmidazolium chloride is attributed to calcium aggravation, oxidative and nitrosative stress, and apoptosis

Sandeep Kumar et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Biotechnology & Applied Microbiology

Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells

Martin Loignon et al.

BMC BIOTECHNOLOGY (2008)

Article Chemistry, Medicinal

Comprehensive mechanistic analysis of hits from high-throughput and docking screens against β-lactamase

Kerim Babaoglu et al.

JOURNAL OF MEDICINAL CHEMISTRY (2008)

Article Biochemical Research Methods

Lifeact: a versatile marker to visualize F-actin

Julia Riedl et al.

NATURE METHODS (2008)

Article Genetics & Heredity

Spectrin mutations cause spinocerebellar ataxia type 5

Y Ikeda et al.

NATURE GENETICS (2006)

Article Urology & Nephrology

Mutational and biological analysis of α-actinin-4 in focal segmental glomerulosclerosis

A Weins et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)

Article Oncology

Structure-activity studies on gossypol in tumor cell lines

MD Shelley et al.

ANTI-CANCER DRUGS (2000)