Photoredox/Nickel Dual Catalysis for the C(sp3)-C(sp3) Cross-Coupling of Alkylsilicates with Alkyl Halides

Alkylsilicates were engaged under photoredox/nickel dual catalysis conditions with alkyl halides for the first time. The C(sp(3))-C(sp(3)) cross-coupling products were obtained in moderate yields and were accompanied by the homocoupling products of the alkyl halide derivatives. These promising findings are strongly suggestive of the high synthetic potential of the dual catalytic approach for the forging of alkyl carbon-carbon bonds.