4.6 Article

Role of inflammation in depression and anxiety: Tests for disorder specificity, linearity and potential causality of association in the UK Biobank

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Psychiatry

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms A Genetic Correlation and 2-Sample Mendelian Randomization Study

Nils Kappelmann et al.

Summary: This study found genetic overlap between CRP levels and individual depressive symptoms, and IL-6 signaling could potentially be associated with suicidality. BMI may be causally associated with four other depressive symptoms.

JAMA PSYCHIATRY (2021)

Article Immunology

Depression and interleukin-6 signaling: A Mendelian Randomization study

Kristen M. Kelly et al.

Summary: The study using Mendelian Randomization found a causal relationship between soluble interleukin-6 receptor and depression, potentially through different signaling pathways. The results suggest involvement of the IL-6 signaling pathway in depression and further research is needed.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Article Multidisciplinary Sciences

Genetic predictors of participation in optional components of UK Biobank

Jessica Tyrrell et al.

Summary: This study investigated genetic factors affecting participation in large studies such as the UK Biobank, finding that some participation factors may have underlying genetic components. Genetic correlations showed that participation bias is common across studies. Mendelian randomization revealed that factors such as educational duration and certain health conditions can influence participation rates.

NATURE COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

Association of inflammation with depression and anxiety: evidence for symptom-specificity and potential causality from UK Biobank and NESDA cohorts

Yuri Milaneschi et al.

Summary: The study found inflammation to be uniformly associated with core depressive symptoms of low mood and anhedonia, as well as somatic/neurovegetative symptoms of fatigue, altered sleep, and appetite changes. Inconsistent associations were observed for anxiety. The IL-6/IL-6R pathway may play a causative role in depression.

MOLECULAR PSYCHIATRY (2021)

Article Biochemistry & Molecular Biology

Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Golam M. Khandaker et al.

MOLECULAR PSYCHIATRY (2020)

Letter Cardiac & Cardiovascular Systems

Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes A Mendelian Randomization Study

Marios K. Georgakis et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2020)

Article Multidisciplinary Sciences

Collider bias undermines our understanding of COVID-19 disease risk and severity

Gareth J. Griffith et al.

NATURE COMMUNICATIONS (2020)

Review Psychology, Clinical

Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels

Emanuele Felice Osimo et al.

PSYCHOLOGICAL MEDICINE (2019)

Article Health Care Sciences & Services

Log Odds and the Interpretation of Logit Models

Edward C. Norton et al.

HEALTH SERVICES RESEARCH (2018)

Article Immunology

Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters

Marco Del Giudice et al.

BRAIN BEHAVIOR AND IMMUNITY (2018)

Article Public, Environmental & Occupational Health

Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population

Anna Fry et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2017)

Article Psychiatry

Peripheral cytokine and chemokine alterations in depression: a meta-analysis of 82 studies

C. A. Kohler et al.

ACTA PSYCHIATRICA SCANDINAVICA (2017)

Article Neurosciences

Low-grade inflammation predicts persistence of depressive symptoms

A. Zalli et al.

PSYCHOPHARMACOLOGY (2016)

Review Immunology

IL-6 as a keystone cytokine in health and disease

Christopher A. Hunter et al.

NATURE IMMUNOLOGY (2015)

Review Clinical Neurology

CRP, IL-6 and depression: A systematic review and meta-analysis of longitudinal studies

Vyara Valkanova et al.

JOURNAL OF AFFECTIVE DISORDERS (2013)

Article Neurosciences

A Meta-Analysis of Cytokines in Major Depression

Yekta Dowlati et al.

BIOLOGICAL PSYCHIATRY (2010)

Review Psychiatry

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

M. Bryant Howren et al.

PSYCHOSOMATIC MEDICINE (2009)

Review Neurosciences

From inflammation to sickness and depression: when the immune system subjugates the brain

Robert Dantzer et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Article Medicine, General & Internal

A brief measure for assessing generalized anxiety disorder -: The GAD-7

Robert L. Spitzer et al.

ARCHIVES OF INTERNAL MEDICINE (2006)

Article Health Care Sciences & Services

Monitoring depression treatment outcomes with the patient health questionnaire-9

B Löwe et al.

MEDICAL CARE (2004)

Article Public, Environmental & Occupational Health

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

GD Smith et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2003)