Recent advances and future challenges in the synthesis of 2,4,6-triarylpyridines

2,4,6-Triarylpyridines are key building blocks to access functional molecules that are used in the design of advanced materials, metal-organic frameworks, supramolecules, reactive chemical intermediates and drugs. A number of synthetic protocols to construct this heterocyclic scaffold have been developed to date, the most recent of which (2015-present) are included and discussed in the present review. An emphasis has been placed on the utility of each synthetic approach in view of the scope of aryl/hetaryl substituents, limitations and an outlook of each method to be used in applied sciences.

Automated summary

This review discusses the development of synthetic protocols for 2,4,6-triarylpyridines and emphasizes the utility and limitations of each method in the field of applied sciences.