期刊
THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE
卷 13, 期 -, 页码 -出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/1759720X211041864
关键词
corticosteroid; dactylitis; injection; psoriatic arthritis; tenosynovitis; therapy; treatment; ultrasound
类别
Dactylitis is a common clinical feature in 30-50% of psoriatic arthritis (PsA) patients, serving as a marker for disease severity, independent predictor of cardiovascular morbidity, and impairing motor functions. Current treatment strategies primarily involve corticosteroid injections, with a lack of evidence from randomized controlled trials specifically targeting dactylitis as a primary endpoint.
Dactylitis - a hallmark clinical feature of psoriatic arthritis (PsA) - that occurs in 30-50% of PsA patients, is a marker of disease severity for PsA progression, an independent predictor of cardiovascular morbidity and impairs the motor functions of PsA patients. There is a paucity of evidence for the treatment due to the absence of randomized controlled trials assessing dactylitis as a primary endpoint and current practice arises from the analysis of dactylitis as a secondary outcome. Corticosteroid (CS) injections for dactylitis in PsA patients are a therapeutic treatment option for patients with isolated dactylitis or for patients with flares in tendon sheaths, despite stable and effective systemic treatment. The aim of this narrative review is to briefly illustrate the clinical aspects of dactylitis in PsA, the imaging and clinimetric tools used to diagnose and monitor dactylitis, the current treatment strategies and principally to provide a comprehensive picture of the clinical efficacy and safety with ultrasound-guide and blind techniques of CS injections for dactylitis in PsA patients.
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