期刊
JOURNAL OF CLINICAL MEDICINE
卷 10, 期 17, 页码 -出版社
MDPI
DOI: 10.3390/jcm10173829
关键词
cholangiocarcinoma; liver resection; intrahepatic cholangiocarcinoma; survival; vascular resection
Intrahepatic cholangiocarcinoma (iCCA) usually requires surgical treatment, even in cases of macrovascular invasion, as surgery offers the only chance of cure. However, tumor recurrence is common post-surgery and long-term prognosis is poor, indicating the need for multimodal treatment to improve outcomes.
Intrahepatic cholangiocarcinoma (iCCA) accounts for approximately 10% of all primary liver cancers. Surgery is the only potentially curative treatment, even in cases of macrovascular invasion. Since resection offers the only curative chance, even extended liver resection combined with complex vascular or biliary reconstruction of the surrounding organs seems justified to achieve complete tumour removal. In selected cases, the major vascular resection is the only change to try getting the cure. The best results are achieved by the referral centre with a wide experience in complex liver surgery, such as ALPPS procedure, IVC resection, and ante-situ and ex-situ resections. However, despite aggressive surgery, tumour recurrence occurs frequently and long-term oncological results are very poor. This suggests that significant progress in prognosis cannot be expected by surgery alone. Instead, multimodal treatment including neoadjuvant chemotherapy, radiotherapy, and subsequent adjuvant treatment for iCCA seem to be necessary to improve results.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据