期刊
EUROPEAN JOURNAL OF NEUROLOGY
卷 24, 期 9, 页码 1166-1172出版社
WILEY
DOI: 10.1111/ene.13361
关键词
Alzheimer's disease; donepezil; epidemiology; National Health Insurance Research Database; rivastigmine; traditional Chinese medicine
资金
- China Medical University under the Aim for the Top University Plan of the Ministry of Education, Taiwan
- Taiwan Ministry of Health and Welfare Clinical Trial and Research Center of Excellence [MOHW106-TDU-B-212-133004]
- China Medical University Hospital [DMR 101-018]
Background and purposeLarge-scale studies of utilization of medical services among patients with Alzheimer's disease (AD) are lacking. We aimed to investigate the usage of Western medicine and traditional Chinese medicine (TCM) among these patients in Taiwan. MethodsWe analyzed one million samples from the National Health Insurance Research Database in Taiwan. Patients (n=1814) newly diagnosed with AD in 2001-2010 were divided into TCM users (n=528) and non-TCM users (n=1286). ResultsCompared with non-TCM users, TCM users were younger, had a higher female:male ratio and higher utilization rate of Western medicine. The median interval between diagnosis and the first TCM consultation was 7.92months. Donepezil and rivastigmine were commonly prescribed medications. Chinese herbal medicine was the most popular treatment among TCM users. ConclusionsThis study revealed the specific usage patterns of TCM and non-TCM medical services among patients with AD. The information could be used for improving the healthcare of patients with AD.
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