期刊
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
卷 66, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/ijph.2021.1603975
关键词
public health; COVID-19; coronavirus; pandemic; SARS-CoV-2; 2019-nCoV; pneumonia; epidemic
资金
- Wroclaw Medical University [SUB.C290.21.010]
This review aims to summarize the most relevant scientific discoveries on SARS-CoV-2 virus infection, focusing on its pathophysiology and treatment. Through manual examination of research articles, it was found that further studies are crucial to find accurate treatment methods and halt the spread of the disease.
Objectives: The aim of this review is to summarize the most relevant scientific discoveries regarding SARS- CoV-2 virus infection, with the special emphasis put on its pathophysiology and way of treatment. Methods: In November 2020, the research articles have been collected and examined manually to pick the most relevant. In case of fresh topics, e.g. vaccines, we have performed searching using adequate keywords. Preliminary analysis was conducted on 200 manuscripts. Results: Among them 59 papers were out-of-scope, and thus were rejected from the further elaboration. Another 25 papers were rebuffed because they presented topics, that have been extensively described in the already included papers. Basing on the 29 papers we have estimated ratio of observed SARS-CoV-2 infection clinical manifestations and comorbidities among hospitalized patients. 12 papers let us evaluate frequencies of deviations within laboratory markers concentrations, as well as weighted average of the laboratory tests results. Conclusion: Due to the significant infectivity of the virus and its harmfulness towards organism further studies are required to find accurate way of the disease treatment and suspending its spreading.
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