Ozonolysis of α-angelica lactone: a renewable route to malonates

Industrially relevant intermediates such as malonic acid, malonates and 3-oxopropionates can be easily accessed by ozonolysis of alpha-angelica lactone, derived from the platform chemical levulinic acid. The roles of the solvent and of the quenching conditions are of key importance for the outcome of the reaction.

Automated summary

Industrially relevant intermediates such as malonic acid, malonates, and 3-oxopropionates can be easily accessed through ozonolysis of alpha-angelica lactone derived from the platform chemical levulinic acid. The roles of the solvent and quenching conditions are crucial for the outcome of the reaction.