期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 19, 期 39, 页码 8482-8486出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ob01769a
关键词
-
资金
- DFG [DI1536/7-2]
The non-canonical fungal alpha-humulene synthase was studied in terms of its stereochemical processes with isotopic labelling experiments. A new desymmetrisation strategy was developed to allow for a full stereochemical analysis from stereoselectively labelled farnesyl diphosphate to the achiral alpha-humulene product.
The non-canonical fungal alpha-humulene synthase was investigated through isotopic labelling experiments for its stereochemical course regarding inversion or retention at C-1, the face selectivity at C-11, and the stereoselectivity of the final deprotonation. A new and convenient desymmetrisation strategy was developed to enable a full stereochemical analysis of the catalysed steps to the achiral alpha-humulene product from stereoselectively labelled farnesyl diphosphate.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据