4.7 Review

C-H bond functionalization by high-valent cobalt catalysis: current progress, challenges and future perspectives

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Enantioselective Intermolecular Carboamination by C-H Functionalization

Kristers Ozols et al.

Summary: The study presents a method for highly enantioselective intermolecular carboaminations of alkenes through C-H activation catalyzed by high-valent cyclopentadienyl cobalt complexes. This method converts widely available acrylates and bicyclic olefins into enantioenriched isotyrosine derivatives and amino-substituted bicyclic scaffolds under very mild conditions. The reactivity outlined in this research is unique to the (CpCoIII)-Co-x complexes and complements the reactivity of 4d- and 5d- precious-metal catalysts.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Synthesis of Nitrile Bearing Acyclic Quaternary Centers through Co(III)-Catalyzed Sequential C-H Bond Addition to Dienes and N-Cyanosuccinimide

Sun Dongbang et al.

Summary: In this study, a three-component strategy was disclosed to access quaternary centers bearing nitriles via cobalt-catalyzed C-H bond activation and sequential addition. Various functionalized nitriles were successfully synthesized by using different types of dienes. The synthetic utility of the nitrile products was demonstrated by various transformations, showcasing the potential for further organic synthesis applications.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Inorganic & Nuclear

Strategic evolution in transition metal-catalyzed directed C-H bond activation and future directions

Supriya Rej et al.

Summary: This review summarizes the strategic evolution of directed C-H bond activation chemistry and may stimulate interest in new research areas regarding this significant topic among scientists interested in progress made in the area of directed C-H bond functionalization.

COORDINATION CHEMISTRY REVIEWS (2021)

Article Chemistry, Organic

Directed Cobalt-Catalyzed C-H Activation to Form C-C and C-O Bonds in One Pot via Three-Component Coupling

Meng-Hui Li et al.

Summary: An efficient cobalt-catalyzed three-component coupling reaction is disclosed, which can construct C(sp(2))-C(sp(3)) and C-O bonds in one-pot with high yields and functional group compatibility. Mechanistic studies suggest a radical process may be involved in the reaction.

ORGANIC LETTERS (2021)

Article Chemistry, Organic

Cobalt-Catalyzed Direct C-H Carbonylative Synthesis of Free (NH)-Indolo[1,2-a]quinoxalin-6(5H)-ones

Qian Gao et al.

Summary: A cobalt-catalyzed direct CH carbonylative reaction of N-(2-(1H-indol-1-yl)phenyl)picolinamides for the synthesis of (NH)-indolo[1,2-a]quinoxalin-6(5H)-one skeletons has been developed. Various free (NH)-indolo[1,2-a]quinoxalin-6(5H)-ones were obtained in good yields (up to 88%) using benzene-1,3,5-triyl triformate (TFBen) as the CO source and picolinamide as the traceless directing group. Additionally, a series of product derivatizations were demonstrated, and the core fragment of PARP-1 inhibitor C can be readily constructed by this protocol.

ORGANIC LETTERS (2021)

Article Chemistry, Organic

Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates Under Cobalt Catalysis

Paula Amanda Zagorska et al.

Summary: The study focuses on cobalt-catalyzed C-H functionalization of phenylglycine derivatives with alkynes, investigating various cobalt catalysts, oxidants, base additives, and reaction solvents in order to find conditions for 1,2-dihydroisoquinoline synthesis with acceptable yield.

CHEMISTRY OF HETEROCYCLIC COMPOUNDS (2021)

Article Chemistry, Organic

Thioamide-Directed Cp*Co(III)-Catalyzed C-H Allylation of Ferrocenes

Zhuo-Zhuo Zhang et al.

Summary: In this study, the first Cp*Co(III)-catalyzed C-H allylation of ferrocene thioamides with allyl carbonates was developed. The reaction is compatible with a wide range of functional groups, providing various allylated ferrocene derivatives in up to 90% yields. Mechanistic studies showed that the thiocarbonyl-directing group plays a crucial role in C-H activation.

ORGANIC LETTERS (2021)

Article Chemistry, Organic

Transition metal-catalyzed synthesis of N, O-Heterocycles via C-H functionalization

Togati Naveen

Summary: Heterocyclic compounds are widely present in natural products, pharmaceuticals, and agrochemicals, and the synthesis of these compounds through C-H activation has made impressive advances as a newly emerging synthetic strategy. Transition metal catalyzed C-H bond activation without pre-functionalized starting materials has become a powerful tool for creating diverse heterocycles.

TETRAHEDRON (2021)

Article Chemistry, Multidisciplinary

C-H Activation: Toward Sustainability and Applications

Toryn Dalton et al.

Summary: The field of green chemistry has been evolving for over two decades, with a focus on conserving natural resources and protecting the environment through judicious synthetic routes and materials choices. Current research efforts are aimed at overcoming sustainability challenges in C-H activation, including seeking abundant metal catalysts and introducing bio-derived solvents. Industrial uptake will be crucial for the future growth of this field, urging researchers to strive towards sustainable C-H activation.

ACS CENTRAL SCIENCE (2021)

Review Chemistry, Multidisciplinary

Transition-metal-catalyzed C-H allylation reactions

Subhabrata Dutta et al.

Summary: Allylation reactions, pioneered by Tsuji and Trost, are essential C-C bond-forming transformations with broad applications in synthetic chemistry, bioactive compounds, and pharmaceutical industries. The development of synthetic strategies and the emergence of site-selective C-H activation have further expanded the scope of allylation reactions, eliminating the need for pre-functionalized substrates and activated allylating reagents.
Article Chemistry, Organic

Cobalt-Catalyzed C(sp2)-H Carbonylation of Amino Acids Using Picolinamide as a Traceless Directing Group

Lukass Lukasevics et al.

Summary: An efficient protocol for the C(sp(2))-H carbonylation of amino acid derivatives based on an inexpensive cobalt(II) salt catalyst is reported. The method utilizes picolinamide as a traceless directing group and Co(dpm)(2) as the catalyst, allowing for a broad range of phenylalanine derivatives bearing diverse functional groups to be tolerated. Moreover, the method can be successfully applied for the C(sp(2))-H carbonylation of short peptides, enabling access for peptide late-stage carbonylation.

ORGANIC LETTERS (2021)

Review Multidisciplinary Sciences

Arene diversification through distal C(sp2)-H functionalization

Uttam Dutta et al.

Summary: This review summarizes recent elegant discoveries in controlling distal C-H activation through directing group assistance, transient mediators or traceless directors, noncovalent interactions, and catalyst and/or ligand selection.

SCIENCE (2021)

Article Chemistry, Physical

Recent Advances in External-Directing-Group-Free C-H Functionalization of Carboxylic Acids without Decarboxylation

Jayabrata Das et al.

Summary: Selective functionalization of C-H bonds is a crucial topic in organic synthesis, utilizing the abundant portion of a molecule for synthetic manipulations. Utilizing native carboxylate groups for C-H activation can eliminate the need for exogenous directing groups, increasing reaction diversity. The coverage of carboxylate-aided functionalizations of organic molecules without decarboxylation is expected to be unique and beneficial for researchers in academia and industry.

ACS CATALYSIS (2021)

Review Chemistry, Physical

Traceless Directing Groups in Sustainable Metal-Catalyzed C-H Activation

Athanasios Zarkadoulas et al.

Summary: This review article summarizes the work done on TDG-assisted catalysis with manganese, iron, cobalt, nickel, or copper catalysts, and discusses the structure-activity relationships observed, by presenting the catalytic pathways and range of transformations reported thus far.

CATALYSTS (2021)

Review Chemistry, Inorganic & Nuclear

Metal-Catalyzed C(sp2)-H Functionalization Processes of Phenylalanine- and Tyrosine-Containing Peptides

Arkaitz Correa

Summary: The challenge of site-selective chemical diversification of biomolecules is important in medicinal chemistry and chemical biology. Functionalizing unreactive C-H bonds has the potential to simplify chemical syntheses. Metal-catalyzed peptide labelling techniques and site-selective modification challenges are discussed, with promising strategies highlighted for late-stage diversification of peptides through 6-membered metallacycles formation.

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY (2021)

Article Chemistry, Organic

Cobalt-catalyzed C-H bond functionalization using traceless directing group

Aleksandrs Cizikovs et al.

Summary: Utilizing the traceless directing group (TDG) strategy in transition metal-catalyzed C-H bond functionalization under high valent cobalt catalysis allows for selective and atom-economic construction of C-C and C-heteroatom bonds.

TETRAHEDRON (2021)

Article Chemistry, Organic

Primary amides: Sustainable weakly coordinating groups in transition metal-catalyzed C-H bond functionalization reactions

Rima Thakur et al.

Summary: Primary amides serve as crucial coordinating directing groups for transition-metal catalyzed C-H activation reactions, enabling site-selective activation of ortho-C-H bonds in aromatic compounds, leading to diverse molecular architectures.

TETRAHEDRON (2021)

Review Chemistry, Multidisciplinary

Transient directing ligands for selective metal-catalysed C-H activation

Nupur Goswami et al.

Summary: C-H activation, a transformation perfected by nature through evolution, is a means to expand chemical space by introducing diverse functionalities. The catalytic use of a small molecule as co-catalyst to generate transient directing groups for selective C-H bond cleavage has gained significant attention, providing an efficient route to complex organics.

NATURE REVIEWS CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Late-stage C-H functionalization offers new opportunities in drug discovery

Lucas Guillemard et al.

Summary: In the past decade, the introduction of late-stage functionalization methodologies has significantly advanced the landscape of molecular synthesis. Particularly, C-H functionalization approaches have led to improvements in resource economy and new strategies for drug discovery. However, challenges and limitations in current LSF methods indicate the need for future improvements and development of new approaches.

NATURE REVIEWS CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Directing group migration strategy in transition-metal-catalysed direct C-H functionalization

Yingtao Wu et al.

Summary: Directing group migration has emerged as a practical strategy for transition-metal-catalysed direct C-H activation, leading to highly atom-economical processes and enabling the reusage of directing groups. Progress has been made in developing multitasking directing groups, with the focus on different types of migratable directing groups and their mechanisms, as well as synthetic applications.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Multidisciplinary

Recent development in transition metal-catalysed C-H olefination

Wajid Ali et al.

Summary: Transition metal-catalyzed functionalizations of inert C-H bonds to construct C-C bonds are an ideal route for synthesizing valuable organic molecules. Fine tuning of directing groups, catalysts, and ligands plays a crucial role in selective C-H bond activation. Recent developments in this area have ensured a high level of regioselectivity in C-H olefination reactions.

CHEMICAL SCIENCE (2021)

Article Chemistry, Multidisciplinary

O-Directed C-H functionalization via cobaltacycles: a sustainable approach for C-C and C-heteroatom bond formations

Shyam Kumar Banjare et al.

Summary: This review highlights recent advances in cobalt-catalysed C-H functionalization, emphasizing the use of oxygen atom coordination for sustainable synthesis. While nitrogen-directed functionalizations are well explored, the use of oxygen as a weakly coordinating atom for C-H activation remains largely underdeveloped. The application of cobalt and weakly coordinating directing groups, such as oxygen, shows promise for selective C-H functionalization reactions in the pharmaceutical industry, with potential for further development beyond C-C and C-N bond formation.

CHEMICAL COMMUNICATIONS (2021)

Review Chemistry, Organic

Removal and modification of directing groups used in metal-catalyzed C-H functionalization: the magical step of conversion into 'conventional' functional groups

Renato L. Carvalho et al.

Summary: Regioselective catalytic C-H functionalization has been a useful tool for retrosynthetic disconnections in recent decades. The advancement of the directing group strategy in metal catalyzed synthetic transformations has allowed for a wide range of functionalization reactions, but the success of these methodologies relies on the ease of removing the directing group.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversification of Thiostrepton

Ryan J. Scamp et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Organic

Cp*CoIII/Chiral Carboxylic Acid-Catalyzed Enantioselective 1,4-Addition Reactions of Indoles to Maleimides

Takumaru Kurihara et al.

ASIAN JOURNAL OF ORGANIC CHEMISTRY (2020)

Review Chemistry, Multidisciplinary

Cobalt-Catalyzed Oxidative C-H Activation: Strategies and Concepts

Ruhuai Mei et al.

CHEMSUSCHEM (2020)

Article Chemistry, Organic

Cobalt-Catalyzed, Directed C-H Functionalization/Annulation of Phenylglycinol Derivatives with Alkynes

Jekaterina Bolsakova et al.

JOURNAL OF ORGANIC CHEMISTRY (2020)

Article Chemistry, Physical

Cobalta-Electrocatalyzed C-H Allylation with Unactivated Alkenes

Uttam Dhawa et al.

ACS CATALYSIS (2020)

Article Chemistry, Multidisciplinary

Late-Stage Diversification of Natural Products

Benke Hong et al.

ACS CENTRAL SCIENCE (2020)

Article Chemistry, Multidisciplinary

Cobalt-catalysed C-H methylation for late-stage drug diversification

Stig D. Friis et al.

NATURE CHEMISTRY (2020)

Review Chemistry, Multidisciplinary

Transition Metal Promoted Cascade Heterocycle Synthesis through C-H Functionalization

Alessio Baccalini et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

Article Chemistry, Multidisciplinary

Renewable resources for sustainable metallaelectro-catalysed C-H activation

Ramesh C. Samanta et al.

CHEMICAL SCIENCE (2020)

Review Chemistry, Physical

Transition Metal Catalyzed Enantioselective C(sp2)-H Bond Functionalization

Tapas Kumar Achar et al.

ACS CATALYSIS (2020)

Article Chemistry, Multidisciplinary

Diverse strategies for transition metal catalyzed distal C(sp3)-H functionalizations

Jayabrata Das et al.

CHEMICAL SCIENCE (2020)

Review Chemistry, Multidisciplinary

Traceless directing groups: a novel strategy in regiodivergent C-H functionalization

Geetika Rani et al.

CHEMICAL COMMUNICATIONS (2020)

Review Chemistry, Organic

Cobalt-catalyzed carbonylation of the C-H bond

Lukass Lukasevics et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

N-Iminopyridinium ylide-directed, cobalt-catalysed coupling of sp2C-H bonds with alkynes

Se Hun Kwak et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Multidisciplinary

Cobalt catalyzed electrochemical [4+2] annulation for the synthesis of sultams

Yangmin Cao et al.

GREEN CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Cobaltaelectro-catalyzed oxidative allene annulation by electro-removable hydrazides

Ruhuai Mei et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Multidisciplinary

Cobaltaelectro-Catalyzed C-H Activation with Carbon Monoxide or Isocyanides

Samaresh Chandra Sau et al.

CHEMSUSCHEM (2019)

Article Chemistry, Multidisciplinary

Cobaltaelectro-Catalyzed C-H Acyloxylation

Cong Tian et al.

CHINESE JOURNAL OF CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Chiral Cyclopentadienyl Cobalt(III) Complexes Enable Highly Enantioselective 3d-Metal-Catalyzed C-H Functionalizations

Kristers Ozols et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Organic

Cobalt(III)-Catalyzed [4+2] Annulation of N-Chlorobenzamides with Maleimides

Nachimuthu Muniraj et al.

ORGANIC LETTERS (2019)

Article Chemistry, Multidisciplinary

Biomass-Derived Solvents for Sustainable Transition Metal-Catalyzed C-H Activation

Parthasarathy Gandeepan et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2019)

Article Chemistry, Inorganic & Nuclear

Chiral 2-Aryl Ferrocene Carboxylic Acids for the Catalytic Asymmetric C(sp3)-H Activation of Thioamides

Daichi Sekine et al.

ORGANOMETALLICS (2019)

Review Pharmacology & Pharmacy

An overview of late-stage functionalization in today's drug discovery

Michael Moir et al.

EXPERT OPINION ON DRUG DISCOVERY (2019)

Article Chemistry, Organic

Cobalt-Catalyzed Olefinic C-H Alkenylation/Alkylation Switched by Carbonyl Groups

Tingyan Li et al.

ORGANIC LETTERS (2019)

Article Chemistry, Organic

Cobalt-Catalyzed C(sp2)-H Allylation of Biphenyl Amines with Unbiased Terminal Olefins

Alessio Baccalini et al.

ORGANIC LETTERS (2019)

Article Chemistry, Multidisciplinary

Late-Stage Peptide Diversification through Cobalt-Catalyzed C-H Activation: Sequential Multicatalysis for Stapled Peptides

Melanie M. Lorion et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Enantioselective C(sp3)-H Amidation of Thioamides Catalyzed by a CobaltIII/Chiral Carboxylic Acid Hybrid System

Seiya Fukagawa et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Chemistry, Multidisciplinary

3d Transition Metals for C-H Activation

Parthasarathy Gandeepan et al.

CHEMICAL REVIEWS (2019)

Article Chemistry, Organic

Cp*CoIII-Catalyzed Alkylation of Primary and Secondary C(sp3)-H Bonds of 8-Alkylquinolines with Maleimides

Rakesh Kumar et al.

JOURNAL OF ORGANIC CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Site- selective C( sp3)- H amination of thioamide with anthranils under Cp* CoIII catalysis

Rui-Hua Liu et al.

CHEMICAL COMMUNICATIONS (2019)

Review Chemistry, Organic

Recent advances in cobalt-catalysed C-H functionalizations

Alessio Baccalini et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Electrochemical C-H/N-H Activation by Water-Tolerant Cobalt Catalysis at Room Temperature

Cong Tian et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Coupling of Benzoic Acid C-H Bonds with Alkynes, Styrenes, and 1,3-Dienes

Tung Thanh Nguyen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Tandem C-H Activation/C-C Cleavage/C-H Cyclization of Aromatic Amides with Alkylidenecyclopropanes

Mingliang Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Electrochemical C-H Amination by Cobalt Catalysis in a Renewable Solvent

Nicolas Sauermann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

A Readily Accessible Class of Chiral Cp Ligands and their Application in Ru-II-Catalyzed Enantioselective Syntheses of Dihydrobenzoindoles

Shou-Guo Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Cobalt(II)-Catalyzed Electrooxidative C-H Amination of Arenes with Alkylamines

Xinlong Gao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Electroremovable Traceless Hydrazides for Cobalt-Catalyzed Electro-Oxidative C-H/N-H Activation with Internal Alkynes

Ruhuai Mei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Review Chemistry, Organic

Transient imines as 'next generation' directing groups for the catalytic functionalisation of C-H bonds in a single operation

Sahra St John-Campbell et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Article Multidisciplinary Sciences

Cobalt-catalyzed electrooxidative C-H/N-H [4+2] annulation with ethylene or ethyne

Shan Tang et al.

NATURE COMMUNICATIONS (2018)

Review Chemistry, Multidisciplinary

Combining transition metals and transient directing groups for C-H functionalizations

Trisha Bhattacharya et al.

RSC ADVANCES (2018)

Review Chemistry, Organic

Cobalt-Catalyzed C(sp3)-H Functionalization Reactions

Tatsuhiko Yoshino et al.

ASIAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Chemistry, Organic

Cobalt(III)-Catalyzed [4+2] Annulation of Heterobicyclic Alkenes by sp2 C-H Activation

Arnab Dey et al.

ASIAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Chemistry, Organic

Co(III)-Catalyzed N-chloroamide-directed C-H activation for 3,4-dihydroisoquinolone synthesis

Xiaolong Yu et al.

ORGANIC CHEMISTRY FRONTIERS (2018)

Review Chemistry, Multidisciplinary

Transient Directing Groups for Transformative C-H Activation by Synergistic Metal Catalysis

Parthasarathy Gandeepan et al.

Article Chemistry, Applied

Direct ortho-Acyloxylation of Arenes and Alkenes by Cobalt Catalysis

Cong Lin et al.

ADVANCED SYNTHESIS & CATALYSIS (2018)

Review Chemistry, Multidisciplinary

A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry

Carlo Sambiagio et al.

CHEMICAL SOCIETY REVIEWS (2018)

Article Chemistry, Physical

Electrooxidative Allene Annulations by Mild Cobalt-Catalyzed C-H Activation

Tjark H. Meyer et al.

ACS CATALYSIS (2018)

Article Chemistry, Multidisciplinary

Enantioselective Cobalt(III)-Catalyzed C-H Activation Enabled by Chiral Carboxylic Acid Cooperation

Fabio Pesciaioli et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Applied

Cobalt-Catalyzed Diastereoselective [4+2] Annulation of Phosphinamides with Heterobicyclic Alkenes at Room Temperature

Rajender Nallagonda et al.

ADVANCED SYNTHESIS & CATALYSIS (2018)

Article Chemistry, Multidisciplinary

Isolation of Cp*CoIII-Alkenyl Intermediate in Efficient Cobalt-Catalyzed C-H Alkenylation with Alkynes

Malay Sen et al.

CHEMISTRY-A EUROPEAN JOURNAL (2018)

Review Chemistry, Multidisciplinary

Recent applications of C-H functionalization in complex natural product synthesis

Dylan J. Abrams et al.

CHEMICAL SOCIETY REVIEWS (2018)

Review Chemistry, Multidisciplinary

Palladium-Catalyzed Transformations of Alkyl C-H Bonds

Jian He et al.

CHEMICAL REVIEWS (2017)

Article Chemistry, Organic

Linear Selective C-H Bond Alkylation with Activated Olefins Catalyzed by Cp*CoIII

Nagaraju Barsu et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2017)

Article Chemistry, Organic

Cobalt-Catalyzed Annulation of Amides with Isocyanides via C(sp2)-H Activation

Zheng-Yang Gu et al.

JOURNAL OF ORGANIC CHEMISTRY (2017)

Article Chemistry, Multidisciplinary

Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature

Nicolas Sauermann et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Chemistry, Organic

Cp*Co(III)-Catalyzed Annulation of Carboxylic Acids with Alkynes

Rajib Mandal et al.

ORGANIC LETTERS (2017)

Article Chemistry, Multidisciplinary

Cobalt catalyzed carbonylation of unactivated C(sp3)-H bonds

Nagaraju Barsu et al.

CHEMICAL SCIENCE (2017)

Article Chemistry, Multidisciplinary

Cobalt-catalysed C-H carbonylative cyclisation of aliphatic amides

Patrick Williamson et al.

CHEMICAL SCIENCE (2017)

Article Chemistry, Physical

Cobalt(III)-Catalyzed Hydroarylation of Allenes via C-H Activation

Sachiyo Nakanowatari et al.

ACS CATALYSIS (2017)

Article Chemistry, Organic

Cobalt-catalyzed C-H activation and regioselective intermolecular annulation with allenes

Tianlei Li et al.

ORGANIC CHEMISTRY FRONTIERS (2017)

Article Chemistry, Multidisciplinary

Cp*CoIII-Catalyzed Bis-isoquinolone Synthesis by C-H Annulation of Arylamide with 1,3-Diyne

Malay Sen et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

Article Chemistry, Multidisciplinary

Thioamide-Directed Cobalt(III)-Catalyzed Selective Amidation of C(sp3)-H Bonds

Peng Wen Tan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Review Chemistry, Inorganic & Nuclear

Cobalt(II)-catalyzed C-H functionalization using an N,N′-bidentate directing group

Yadagiri Kommagalla et al.

COORDINATION CHEMISTRY REVIEWS (2017)

Article Chemistry, Applied

Traceless Directing Group Assisted Cobalt-Catalyzed C-H Carbonylation of Benzylamines

Fei Ling et al.

ADVANCED SYNTHESIS & CATALYSIS (2017)

Article Chemistry, Multidisciplinary

Synthesis of Bicyclo[n.1.0]alkanes by a Cobalt-Catalyzed Multiple C(sp3)-H Activation Strategy

Zhuo-Zhuo Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Applied

Cobalt(III)-Catalyzed Alkylation of Primary C(sp3)-H Bonds with Diazo Compounds

Sheng-Yi Yan et al.

ADVANCED SYNTHESIS & CATALYSIS (2017)

Article Chemistry, Multidisciplinary

Full Selectivity Control in Cobalt(III)-Catalyzed C-H Alkylations by Switching of the C-H Activation Mechanism

Daniel Zell et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

A Convergent Synthesis of Functionalized Alkenyl Halides through Cobalt(III)-Catalyzed Three-Component C-H Bond Addition

Jeffrey A. Boerth et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Stereoselective Synthesis of Tetrasubstituted Alkenes via a Cp*CoIII-Catalyzed C-H Alkenylation/Directing Group Migration Sequence

Hideya Ikemoto et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Review Chemistry, Applied

Mild Cobalt(III)-Catalyzed C-H Hydroarylation of Conjugated C=C/C=O Bonds

Jie Li et al.

ADVANCED SYNTHESIS & CATALYSIS (2017)

Article Chemistry, Multidisciplinary

Aminoquinoline-directed, cobalt-catalyzed carbonylation of sulfonamide sp2 C-H bonds

Tung Thanh Nguyen et al.

CHEMICAL COMMUNICATIONS (2017)

Review Chemistry, Multidisciplinary

C-H functionalization by high-valent Cp*Co(III) catalysis

Shan Wang et al.

CHEMICAL COMMUNICATIONS (2017)

Article Chemistry, Multidisciplinary

Cobalt-catalyzed aryl C-H activation and highly regioselective intermolecular annulation of sulfonamides with allenes

Neetipalli Thrimurtulu et al.

CHEMICAL COMMUNICATIONS (2017)

Article Chemistry, Applied

Cobalt-Catalyzed Direct Amination of Arenes with Alkylamines via Bidentate-Chelation Assistance

Qiangqiang Yan et al.

ADVANCED SYNTHESIS & CATALYSIS (2016)

Article Chemistry, Applied

Easy Access to 1-Amino and 1-Carbon Substituted Isoquinolines via Cobalt-Catalyzed C-H/N-O Bond Activation

Krishnamoorthy Muralirajan et al.

ADVANCED SYNTHESIS & CATALYSIS (2016)

Article Chemistry, Multidisciplinary

Unnatural Amino Acid Synthesis Enabled by the Regioselective Cobalt(III)-Catalyzed Intermolecular Carboamination of Alkenes

Andreas Lerchen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed sp2-C-H Activation: Intermolecular Heterocyclization with Allenes at Room Temperature

Neetipalli Thrimurtulu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cationic Cobalt(III) Catalyzed Indole Synthesis: The Regioselective Intermolecular Cyclization of N-Nitrosoanilines and Alkynes

Yujie Liang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Oxidative C-H/C-H Cross-Coupling between Two Heteroarenes

Guangying Tan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Redox-Neutral Synthesis of Unprotected Indoles Featuring an N-N Bond Cleavage

Andreas Lerchen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Highly Stereoselective Cobalt(III)-Catalyzed Three-Component C-H Bond Addition Cascade

Jeffrey A. Boerth et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cobalt-catalyzed chelation assisted C-H allylation of aromatic amides with unactivated olefins

Takuma Yamaguchi et al.

CHEMICAL COMMUNICATIONS (2016)

Review Chemistry, Multidisciplinary

Mild metal-catalyzed C-H activation: examples and concepts

T. Gensch et al.

CHEMICAL SOCIETY REVIEWS (2016)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Intramolecular Cross-Dehydrogenative C-H/X-H Coupling: Efficient Synthesis of Indoles and Benzofurans

Jayanta Ghorai et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Cyclization of N-Methoxy Benzamides with Alkynes using an Internal Oxidant through C-H/N-O Bond Activation

Ganesan Sivakumar et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Article Chemistry, Multidisciplinary

Cp*CoIII-Catalyzed C(sp3)-H Bond Amidation of 8-Methylquinoline

Nagaraju Barsu et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Editorial Material Chemistry, Organic

Recent Advances in C-H Functionalization

Huw M. L. Davies et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

Article Chemistry, Organic

Cobalt-promoted selective arylation of benzamides and acrylamides with arylboronic acids

Liang Hu et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2016)

Article Chemistry, Organic

Co(III)-Catalyzed, Internal and Terminal Alkyne-Compatible Synthesis of Indoles

Shuguang Zhou et al.

ORGANIC LETTERS (2016)

Article Chemistry, Organic

Cobalt(II)-Catalyzed C-H Amination of Arenes with Simple Alkylamines

Lin-Bao Zhang et al.

ORGANIC LETTERS (2016)

Article Chemistry, Organic

Cobalt(III)-catalyzed efficient synthesis of indenones through carboannulation of benzoates and alkynes

Lingheng Kong et al.

ORGANIC CHEMISTRY FRONTIERS (2016)

Review Chemistry, Multidisciplinary

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon-Hydrogen Bonds

Olafs Daugulis et al.

ACCOUNTS OF CHEMICAL RESEARCH (2015)

Article Chemistry, Multidisciplinary

Dehydrative Direct C-H Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis

Yudai Suzuki et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Aryl and Alkenyl C-H Aminocarbonylation with Isocyanates and Acyl Azides

Jie Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Directed C-H Coupling with Diazo Compounds: Straightforward Access towards Extended π-Systems

Dongbing Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Dehydrative [4+2] Annulation of Oxime with Alkyne by CH and NOH Activation

Malay Sen et al.

CHEMISTRY-A EUROPEAN JOURNAL (2015)

Article Chemistry, Multidisciplinary

C-H Activation/Functionalization Catalyzed by Simple, Well-Defined Low-Valent Cobalt Complexes

Brendan J. Fallon et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Cyclization of Aliphatic Amides and Terminal Alkynes with Silver-Cocatalyst

Jitan Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Organic

Cobalt(III)-Catalyzed Directed C-H Allylation

Tobias Gensch et al.

ORGANIC LETTERS (2015)

Article Chemistry, Organic

Cobalt(III)-Catalyzed C-H Bond Amidation with Isocyanates

Joshua R. Hummel et al.

ORGANIC LETTERS (2015)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed C(sp2)-H Alkoxylation of Aromatic and Olefinic Carboxamides

Lin-Bao Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed C-H Cyanation of Arenes and Heteroarenes

Jie Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Multidisciplinary

Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C-H Bond Functionalization/Addition/Cyclization Cascades

Joshua R. Hummel et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Review Chemistry, Multidisciplinary

Low-Valent Cobalt Catalysis: New Opportunities for C-H Functionalization

Ke Gao et al.

ACCOUNTS OF CHEMICAL RESEARCH (2014)

Review Chemistry, Applied

Weakly Coordinating Directing Groups for Ruthenium(II)-Catalyzed C-H Activation

Suman De Sarkar et al.

ADVANCED SYNTHESIS & CATALYSIS (2014)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed, Aminoquinoline-Directed C(sp2)-H Bond Alkenylation by Alkynes

Liene Grigorjeva et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Review Chemistry, Multidisciplinary

Development of Cobalt-Catalyzed C-H Bond Functionalization Reactions

Naohiko Yoshikai

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2014)

Article Chemistry, Multidisciplinary

Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C-H Alkenylation/Annulation Sequence

Hideya Ikemoto et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Multidisciplinary

Co(III)-Catalyzed C-H Activation/Formal SN-Type Reactions: Selective and Efficient Cyanation, Halogenation, and Allylation

Da-Gang Yu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Organic

Cobalt-Catalyzed, Aminoquinoline-Directed Coupling of sp2 C-H Bonds with Alkenes

Liene Grigorjeva et al.

ORGANIC LETTERS (2014)

Article Chemistry, Organic

Cobalt-Catalyzed Direct Carbonylation of Aminoquinoline Benzamides

Liene Grigorjeva et al.

ORGANIC LETTERS (2014)

Article Chemistry, Multidisciplinary

A Cationic High-Valent Cp*CoIII Complex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed C-H Bond Activation

Tatsuhiko Yoshino et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Article Chemistry, Multidisciplinary

Cp*CoIII-Catalyzed C2-Selective Addition of Indoles to Imines

Tatsuhiko Yoshino et al.

CHEMISTRY-A EUROPEAN JOURNAL (2013)

Review Chemistry, Multidisciplinary

Weak Coordination as a Powerful Means for Developing Broadly Useful C-H Functionalization Reactions

Keary M. Engle et al.

ACCOUNTS OF CHEMICAL RESEARCH (2012)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Hydroarylation of Alkynes through Chelation-Assisted C-H Bond Activation

Ke Gao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)