期刊
GELS
卷 7, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/gels7030126
关键词
periprosthetic joint infection; fracture related infection; osteomyelitis; coating; antibacterial hydrogel; open fractures; infection; osteosynthesis; gentamicin-coated nail; antibiotic-coated nail
Implant related infection is a common complication in orthopaedic and trauma surgery, with local antibiotic treatment strategies becoming increasingly important. While there are two available coatings on the market, their therapeutic use is less explored, though current evidence indicates their efficacy in prophylaxis against infections. This article aims to summarize recent evidence on the clinical application of antibacterial hydrogels and coatings, as well as suggest potential future applications.
Implant related infection is one of the most frequent complications in orthopaedic and trauma surgery. Local antibiotic treatment strategies are becoming part of the prevention and treatment methodology for this fearful complication. To date, there are two coatings available on the market, both with a polylactic acid base. Current evidence supports the use of these types of coatings in the prophylaxis of periprosthetic infections and fracture-related infections. However, their therapeutic use has been less investigated. The purpose of this article is to summarise recent evidence relating to the clinical application of antibacterial hydrogels and coatings in orthopaedic and traumatology surgery and indicating which future applications may benefit from it.
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