期刊
JOURNAL OF VETERINARY RESEARCH
卷 65, 期 3, 页码 361-368出版社
SCIENDO
DOI: 10.2478/jvetres-2021-0035
关键词
dairy cow; negative energy balance; plasma; follicle
资金
- National Science Foundation Committee of China [31772804]
- Heilongjiang Bayi Agriculture University graduate student innovation fund project [YJSCX2019-Y38]
The study found that negative energy balance in early postpartum cows resulted in decreased body condition, lower milk yield, and significant changes in energy metabolite, hormone and cytokine concentrations in the blood, leading to a lower follicular growth rate.
Introduction: The aim of this study was to evaluate the effect of negative energy balance (NEB) on the final growth of the dominant ovarian follicle in Holstein cows. Material and Methods: Cows at 14 to 21 d postpartum from an intensive dairy farm were randomly selected and allocated into a positive energy balance group (PEB, with beta-hydroxybutyric acid (BHBA) level < 1.2 mmol/L, n = 15) and an NEB group (BHBA > 1.2 mmol/L, n = 15). Plasma samples were collected at 21, 50 and 55 d postpartum to assess the concentrations of energy metabolites, minerals, hormones and cytokines. Ovaries were examined by transrectal ultrasound on days 50 and 55 (120 hours later) to evaluate the diameter of the largest follicle. Results: Compared with PEB cows, there were a more severe body condition loss and a lower milk yield in NEB cows (P < 0.05) and these had greater concentrations of plasma BHBA, non-esterified fatty acids, triglycerides, urea nitrogen, growth hormone, interleukin 6, and fibroblast growth factor 21 and lesser concentrations of plasma glucose, total cholesterol, insulin, insulin-like growth factor 1, insulin-like growth factor binding protein 3, leptin, brain-derived neurotrophic factor and angiopoietin-like protein 8 on d 21 (P < 0.05), while plasma minerals were not affected by energy status (P > 0.05). These changes persisted until the end of the study period (50-55 days postpartum) resulting in a lower follicular growth rate for cows in the NEB than the PEB group. Conclusion: These observations indicate that follicular growth rate is associated with measurable changes in energy metabolite, hormone and cytokine concentrations caused by early postpartum NEB.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据