Gender Differences in Neuropsychiatric Symptoms Among Community-Dwelling Mexican Americans Aged 80 and Older

Background and Objectives To assess gender differences in prevalence of neuropsychiatric symptoms (NPS) among community-dwelling Mexican Americans >= 80 years. Research Design and Methods Using data from Wave 7 (2010-2011) of the Hispanic Established Population for the Epidemiological Study of the Elderly, we analyzed the NPS of 914 participants as determined by the Neuropsychiatric Inventory (NPI) with assessments conducted by their caregivers. Multivariate logistic regression models were used to test the association of individual NPS with gender, adjusting for relevant characteristics. Results The average age of our sample was 86.1 years, and 65.3% were women. Over 60% of participants had at least one informant/caregiver reported NPS. After adjustment, women had lower odds than men of agitation/aggression but higher odds of dysphoria/depression and anxiety. Discussion Recognizing gender differences in NPS phenotype could help guide development of culturally appropriate NPS screening and treatment programs.

Automated summary

The study found that among Mexican American community-dwelling individuals aged 80 and above, women were more likely to have dysphoria/depression and anxiety, while men had lower odds of agitation/aggression. Recognizing these gender differences in neuropsychiatric symptoms could help tailor appropriate screening and treatment programs.