Magnetic nanoporous MCM-41 supported melamine: A powerful nanocatalyst for synthesis of biologically active 2-amino-3-cyanopyridines

A novel core-shell structured magnetic nanocomposite supported melamine with mesoporous silica shell and magnetite core (Fe3O4 @MCM-41/Melamine) was synthesized and used as powerful nano-organocatalyst for preparation of 2-amino-3-cyanopyridines. The Fe3O4@MCM-41/Melamine was synthesized via chemical grafting of propylmelamine groups on Fe3O4@MCM-41 nanocomposite. The structural and chemical characteristics of the Fe3O4 @MCM-41/Melamine were studied using Fourier transform infrared (FT-IR) spectroscopy, vibrating sample magnetometer (VSM), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM) and energydispersive X-ray (EDX) techniques. The Fe3O4 @MCM-41/Melamine was used as powerful catalyst for preparation of 2-amino-3-cyanopyridines in water. This nanocatalyst was magnetically recovered and reused several times with keeping its efficiency.

Automated summary

A novel core-shell structured magnetic nanocomposite supported melamine with mesoporous silica shell and magnetite core was synthesized and used as a powerful nano-organocatalyst for preparation of 2-amino-3-cyanopyridines. The nanocatalyst showed efficient catalytic activity in water and could be magnetically recovered and reused multiple times while maintaining its efficiency.