Phosphomatics: interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets

Motivation: Mass spectrometry-based phosphoproteomics can routinely identify and quantify thousands of phosphorylated peptides from a single experiment. However interrogating possible upstream kinases and identifying key literature for phosphorylation sites is laborious and time-consuming. Results: Here, we present Phosphomatics-a publicly available web resource for interrogating phosphoproteomics data. Phosphomatics allows researchers to upload phosphoproteomics data and interrogate possible relationships from a substrate-, kinase- or pathway-centric viewpoint.

Automated summary

Phosphomatics is a publicly available web resource for investigating phosphoproteomics data and allows researchers to explore relationships of phosphorylation sites from different perspectives. Researchers can upload and analyze phosphoproteomics data through Phosphomatics to identify possible upstream kinases and pathways for further study.