期刊
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
卷 47, 期 3, 页码 241-249出版社
WILEY
DOI: 10.1111/eci.12730
关键词
Autonomic nervous system; BMI; cardiometabolic risk; hypertension; personal prevention; smoke
Background This study addresses whether a unitary cardiac autonomic nervous system index (ANSI), obtained combining multiple metrics from heart rate variability (HRV) into a radar plot could provide an easy appreciation of autonomic performance in a clinical setting. Materials and Methods Data are standardized using percentile ranking of autonomic proxies from a relatively large reference population (n = 1593, age 39 13 years). Autonomic indices are obtained from autoregressive spectral analysis of (ECG derived) HRV at rest and during standing up. A reduced ANSI (using RR, RR variance and rest-stand difference of LFnu) is then constructed as a radar plot, quantified according to its combined area and tested against different risk subgroups. Results With growing risk profile, there is a marked reduction of the rank value of ANSI, quantified individually by the radar plot area. The practical usefulness of the approach was tested in small groups of additional subjects putatively characterized by elevated or poor autonomic performance. Data show that elite endurance athletes are characterized by elevated values of ANSI (80.6 +/- 14.9, P < 0.001) while subjects with either Type 1 or Type 2 diabetes show lower values (DM1 = 37.0 +/- 18.9 and DM2 = 26.8 +/- 23.3, P = 0.002), and patients with coronary artery disease (CAD) represent a nadir (17 +/- 20, P < 0.001). Conclusions This observational study shows the feasibility of testing simpler metrics of cardiac autonomic regulation based on a multivariate unitary index in a preventive setting. This simple approach might foster a wider application of HRV in the clinical arena, and permit an easier appreciation of autonomic performance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据