Analysis and evaluation of the efficacy of ultrasound-guided microwave ablation for papillary thyroid microcarcinoma

Objective The choice of the most appropriate therapeutic approach for a diagnosed papillary thyroid microcarcinoma (PTMC) remains controversial. The present study aimed to evaluate the efficacy of microwave ablation (MWA) for unifocal PTMC with a diameter of <= 0.6 cm. Methods A total of 63 consecutive patients with PTMC treated with MWA were studied retrospectively. MWA was performed using the hydrodissection technique and multidimensional fixed-needle principle. We analyzed the absorption of the MWA area and evaluated the prognosis over a follow-up period of 24 months. In addition, 83 patients with PTMC who underwent surgery were selected. The operating room characteristics and procedural complications of the two groups were compared. Results In the MWA group, the volume of nodules (p < 0.05) decreased from 0.04 +/- 0.03 cm(3) to 0.0001 +/- 0.0004 cm(3) at the 24-month follow-up after MWA, and the volume reduction rate (p < 0.05) was 99.43 +/- 1.58%. The incidence of temporary reactive hyperplastic lymphadenectasis was higher and that of other complications was lower in the MWA group than in the surgery group. One percent of the patients in the surgery group had recurrence or metastasis, but none were detected in the MWA group. The loss of thyroid tissue volume (p < 0.001), operating room time (p < 0.001), and the mean length of hospital stay (p < 0.001) were significantly lower in the MWA group than in the surgery group. Conclusion Ultrasound-guided MWA is an effective treatment strategy for unifocal PTMC with a diameter of <= 0.6 cm.

Automated summary

Ultrasound-guided MWA is an effective treatment strategy for unifocal PTMC with a diameter of <= 0.6cm. The volume of nodules significantly decreased in the MWA group after treatment, with lower rates of complications than surgery, and shorter operating room time and hospital stay.