4.4 Review

A Narrative Review: In-vitro Methods for Assessing Bio-Accessibility/Bioavailability of Iron in Plant-Based Foods

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FRONTIERS MEDIA SA
DOI: 10.3389/fsufs.2021.727533

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in-vitro; iron; bioavailability; bio-accessibility; INFOGEST

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This review discusses in-vitro methods of iron bioavailability in plant-based foods, focusing on the effects of inhibitors and processing on the iron bioavailability. It also includes updates on a recent INFOGEST method used to measure the bioavailability of iron in plant-based foods.
In-vitro measurement has the advantage of rapid and convenient method of screening the iron bioavailability within the range of plant-based foods. It is important to do preliminary screening as it provides information which will be useful to identify promising plant sources of iron before moving to human trials. A review on in-vitro methods of bio-accessibility and bioavailability of iron in plant-based foods including fruits, vegetables, cereals and legumes is entailed here. The review will focus on in-vitro methods of iron bioavailability in plant-based foods and the effects of inhibitors and processing on the iron bioavailability. The variation of the methods and updates on a recent INFOGEST method used to measure the bioavailability of iron in plant-based foods will also be discussed.

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