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Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016-2017

期刊

EMERGING INFECTIOUS DISEASES
卷 27, 期 11, 页码 2971-2973

出版社

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2711.211575

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资金

  1. Centers for Disease Control and Prevention's Advanced Molecular Detection Program
  2. Yale University's School of Public Health
  3. Yale University's Jackson Institute of Global Health Field Experience Award
  4. Yale Collaborative Action Fellowship

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The study revealed that the 2016-2017 Zika virus epidemic in Puerto Rico was driven by multiple introductions, spreading across the island, complex evolutionary patterns, and approximately 10 months of cryptic transmission.
We reconstructed the 2016-2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic's origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns, and approximate to 10 months of cryptic transmission.

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