4.5 Review

Engineering chromosome rearrangements in cancer

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation

Carina Heydt et al.

Summary: Gene fusions are important targets for cancer therapy in lung cancer. RNA-based parallel sequencing methods are potent tools for reliable detection of targetable gene fusions in clinical diagnostics. DNA-based methods also show promise but may result in more false positive results.

BMC MEDICAL GENOMICS (2021)

Article Gastroenterology & Hepatology

Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma

Kenta Kawasaki et al.

GASTROENTEROLOGY (2020)

Article Multidisciplinary Sciences

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Esther Rheinbay et al.

NATURE (2020)

Article Multidisciplinary Sciences

Patterns of somatic structural variation in human cancer genomes

Yilong Li et al.

NATURE (2020)

Article Biochemical Research Methods

CRISPR off-target detection with DISCOVER-seq

Beeke Wienert et al.

NATURE PROTOCOLS (2020)

Article Biochemical Research Methods

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

Erwei Zuo et al.

NATURE PROTOCOLS (2020)

Article Biotechnology & Applied Microbiology

Optimized base editors enable efficient editing in cells, organoids and mice

Maria Paz Zafra et al.

NATURE BIOTECHNOLOGY (2018)

Article Medicine, General & Internal

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children

A. Drilon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Correction Biochemistry & Molecular Biology

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (vol 174, pg 758, 2018)

David A. Quigley et al.

Article Gastroenterology & Hepatology

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

John Hilkens et al.

Article Pathology

Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors

Julie W. Reeser et al.

JOURNAL OF MOLECULAR DIAGNOSTICS (2017)

Article Biotechnology & Applied Microbiology

GuideScan software for improved single and paired CRISPR guide RNA design

Alexendar R. Perez et al.

NATURE BIOTECHNOLOGY (2017)

Article Multidisciplinary Sciences

DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma

Edward R. Kastenhuber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target

Peter J. Cook et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects

Benjamin P. Kleinstiver et al.

NATURE (2016)

Article Biotechnology & Applied Microbiology

A versatile reporter system for CRISPR-mediated chromosomal rearrangements

Yingxiang Li et al.

GENOME BIOLOGY (2015)

Article Multidisciplinary Sciences

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

Danilo Maddalo et al.

NATURE (2014)

Article Multidisciplinary Sciences

CRISPR-mediated direct mutation of cancer genes in the mouse liver

Wen Xue et al.

NATURE (2014)

Article Multidisciplinary Sciences

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

Samuel H. Sternberg et al.

NATURE (2014)

Article Medicine, General & Internal

First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer

Benjamin J. Solomon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Medicine, General & Internal

Crizotinib in ROS1-Rearranged Non-Small-Cell Lung Cancer

Alice T. Shaw et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Multidisciplinary Sciences

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

R. Torres et al.

NATURE COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

Targeted genomic rearrangements using CRISPR/Cas technology

Peter S. Choi et al.

NATURE COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran et al.

Article Biochemistry & Molecular Biology

Cancer translocations in human cells induced by zinc finger and TALE nucleases

Marion Piganeau et al.

GENOME RESEARCH (2013)

Article Biotechnology & Applied Microbiology

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Yanfang Fu et al.

NATURE BIOTECHNOLOGY (2013)

Article Multidisciplinary Sciences

Mouse Model for ROS1-Rearranged Lung Cancer

Yasuhito Arai et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong et al.

SCIENCE (2013)

Article Biology

RNA-programmed genome editing in human cells

Martin Jinek et al.

Article Multidisciplinary Sciences

Recurrent R-spondin fusions in colon cancer

Somasekar Seshagiri et al.

NATURE (2012)

Article Multidisciplinary Sciences

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jinek et al.

SCIENCE (2012)

Review Genetics & Heredity

Genome editing with engineered zinc finger nucleases

Fyodor D. Urnov et al.

NATURE REVIEWS GENETICS (2010)

Article Medicine, General & Internal

Anaplastic Lymphoma Kinase Inhibition in Non-Small-Cell Lung Cancer

Eunice L. Kwak et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Cell Biology

Mouse models of human AML accurately predict chemotherapy response

Johannes Zuber et al.

GENES & DEVELOPMENT (2009)

Article Multidisciplinary Sciences

A mouse model for EML4-ALK-positive lung cancer

Manabu Soda et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Medicine, Research & Experimental

Discovery of the Philadelphia chromosome: a personal perspective

Peter C. Nowell

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Oncology

Nucleophosmin and cancer

Silvia Grisendi et al.

NATURE REVIEWS CANCER (2006)

Review Biotechnology & Applied Microbiology

Model organisms - The mighty mouse: genetically engineered mouse models in cancer drug development

Norman E. Sharpless et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Review Genetics & Heredity

Engineering chromosomal rearrangements in mice

YJ Yu et al.

NATURE REVIEWS GENETICS (2001)

Article Medicine, General & Internal

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.

BJ Druker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

Article Biochemistry & Molecular Biology

Two critical hits for promyelocytic leukemia

LZ He et al.

MOLECULAR CELL (2000)

Article Biochemistry & Molecular Biology

Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development

EC Collins et al.

EMBO REPORTS (2000)

Article Multidisciplinary Sciences

Frequent chromosomal translocations induced by DNA double-strand breaks

C Richardson et al.

NATURE (2000)