Recent advances in total syntheses of natural products containing the benzocycloheptane motif

Covering: 2010 to 2020 Benzocycloheptane is a fundamental and unique structural motif found in pharmaceuticals and natural products. The total syntheses of natural products bearing the benzocycloheptane subunit are challenging and there are only a few efficient approaches to access benzocycloheptane. Thus, new methods and innovative strategies for preparing such natural products need to be developed. In this review, recent progress in the total syntheses of natural products bearing the benzocycloheptane motif is presented, and key transformations for the construction of benzocycloheptane are highlighted. This review provides a useful guide for those engaged in the syntheses of natural products containing the benzocycloheptane motif.

Automated summary

This review highlights the recent advances in the total syntheses of natural products containing the benzocycloheptane motif from 2010 to 2020, focusing on key transformations for constructing benzocycloheptane. It provides a useful guide for those engaged in the syntheses of natural products containing the benzocycloheptane motif.