期刊
JOURNAL OF CANCER
卷 12, 期 23, 页码 7003-7009出版社
IVYSPRING INT PUBL
DOI: 10.7150/jca.55803
关键词
acupuncture; electroacupuncture; cancer; surgery; chemotherapy; pain
类别
资金
- National Natural Science Foundation of China [81830052, 31870905, 81673938, 81874436, 81903961]
- Scientific Program of Shanghai Municipal Health Commission [SHWJ2019211]
- Shanghai Municipal Education Commission [ZZJKYX19006]
- Natural Science Foundation of Shanghai [19ZR1424000]
- Construction Project of Shanghai Key Laboratory of Molecular Imaging [18DZ2260400]
- Shanghai Municipal Education Commission (Class II Plateau Disciplinary Construction Program of Medical Technology of SUMHS, 2018-2020)
- School-level Fund [E3-0200-21-201011-73]
- Hundred Teacher Talent Program of Shanghai University of Medicine and Health Sciences
Acupuncture and electroacupuncture have been proven beneficial for cancer patients in alleviating symptoms, reducing treatment-related side-effects, and relieving pain. Further research is needed to clarify the potential mechanisms behind their clinical application.
In addition to cancer-related death, malignant progression also leads to a series of symptoms and side-effects, which would detrimentally affect cancer patients' the quality of life, adversely influence their adherence to treatments, and, therefore, negatively affect their long-term survival. Acupuncture and electroacupuncture (EA), as two classic treatment methods in traditional Chinese medicine, have been widely employed to cure various diseases. Recently, the clinical application of acupuncture and EA in cancer patients has received great attention. In this review, we summarized the clinical application of acupuncture and EA in alleviating the cancer symptoms, reducing the cancer treatment-related side-effects, and relieving the cancer pain. The symptoms and side-effects discussed in this review include fatigue, insomnia, chemotherapy-associated dyspepsia syndrome (CADS), pain, xerostomia, and anxiety and depression. The underlying mechanisms of the therapeutic effects of acupuncture and EA might be related to the regulation of the mitochondrial function, coordination of the activity of the nervous system, adjustment of the production of neurotransmitters, and alleviation of the immune responses. In conclusion, acupuncture and EA have been proved to be beneficial for cancer patients. More research, however, is required to clarify the potential mechanisms behind acupuncture and EA for widespread adoption in clinical application.
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