Natural Plasmodium inui Infections in Humans and Anopheles cracens Mosquito, Malaysia

We detected 2 natural, asymptomatic Plasmodium inui monoinfections in humans in Malaysia by using nested PCR on concentrated high-volume blood samples. We found a P. inui-positive Anopheles cracens mosquito in the same site as the human infections. Investigators should use ultrasensitive detection methods to identify simian malaria parasite transmission in humans.

Automated summary

By using nested PCR on concentrated high-volume blood samples, researchers in Malaysia were able to detect 2 natural, asymptomatic Plasmodium inui monoinfections in humans, as well as a P. inui-positive Anopheles cracens mosquito. To identify simian malaria parasite transmission in humans, investigators should utilize ultrasensitive detection methods.