相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。CRD-733, a Novel PDE9 (Phosphodiesterase 9) Inhibitor, Reverses Pressure Overload-Induced Heart Failure
Daniel A. Richards et al.
CIRCULATION-HEART FAILURE (2021)
Increased Energy Expenditure and Protection From Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9
Ryan P. Ceddia et al.
DIABETES (2021)
Brown adipose tissue is associated with cardiometabolic health
Tobias Becher et al.
NATURE MEDICINE (2021)
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Sumita Mishra et al.
NATURE REVIEWS CARDIOLOGY (2021)
Once-Weekly Semaglutide in Adults with Overweight or Obesity
John P. H. Wilding et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Treatment with atrial natriuretic peptide induces adipose tissue browning and exerts thermogenic actions in vivo
Haruka Kimura et al.
SCIENTIFIC REPORTS (2021)
Obesity Phenotypes, Diabetes, and Cardiovascular Diseases
Marie-Eve Piche et al.
CIRCULATION RESEARCH (2020)
Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction
Mei Methawasin et al.
CIRCULATION-HEART FAILURE (2020)
Cardiac natriuretic peptides
Jens P. Goetze et al.
NATURE REVIEWS CARDIOLOGY (2020)
Increasing Fatty Acid Oxidation Prevents High-Fat Diet-Induced Cardiomyopathy Through Regulating Parkin-Mediated Mitophagy
Dan Shao et al.
CIRCULATION (2020)
Regional adiposity and heart failure with preserved ejection fraction
Vishal N. Rao et al.
EUROPEAN JOURNAL OF HEART FAILURE (2020)
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling
Zhenqi Zhou et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and Is Essential to cGMP-PDE5 Inhibition Efficacy
Nobuaki Fukuma et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2020)
Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease
Dominique Croteau et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2020)
The Importance of Natriuretic Peptides in Cardiometabolic Diseases
Shravya Vinnakota et al.
JOURNAL OF THE ENDOCRINE SOCIETY (2020)
Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity
Maria J. Pereira et al.
DRUGS (2019)
Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration-probing the role of PPARα
James A. Horscroft et al.
FASEB JOURNAL (2019)
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
Mark J. Ranek et al.
NATURE (2019)
Obesity: global epidemiology and pathogenesis
Matthias Blueher
NATURE REVIEWS ENDOCRINOLOGY (2019)
Impact of different ectopic fat depots on cardiovascular and metabolic diseases
Daniele Ferrara et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Weight loss variability with SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes mellitus and obesity: Mechanistic possibilities
Emily Brown et al.
OBESITY REVIEWS (2019)
Atrial Natriuretic Peptide: A Molecular Target of Novel Therapeutic Approaches to Cardio-Metabolic Disease
Valentina Cannone et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
C. Ronald Kahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction
S. D. Solomon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Phosphodiesterase 9A in Brain Regulates cGMP Signaling Independent of Nitric-Oxide
John F. Harms et al.
FRONTIERS IN NEUROSCIENCE (2019)
Effects of sacubitril/valsartan on neprilysin targets and the metabolism of natriuretic peptides in chronic heart failure: a mechanistic clinical study
Helene Nougue et al.
EUROPEAN JOURNAL OF HEART FAILURE (2019)
Obesity and cardiovascular disease: revisiting an old relationship
Chrysi Koliaki et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2019)
Fenofibrate induced PPAR alpha expression was attenuated by oestrogen receptor alpha overexpression in Hep3B cells
Long-Bin Jeng et al.
ENVIRONMENTAL TOXICOLOGY (2018)
Natriuretic peptides promote glucose uptake in a cGMP-dependent manner in human adipocytes
Marine Coue et al.
SCIENTIFIC REPORTS (2018)
Pivotal Role of Excess Intra-Abdominal Adipose in the Pathogenesis of Metabolic/Obese HFpEF
Dalane W. Kitzman et al.
JACC-HEART FAILURE (2018)
The effects of oestrogens and their receptors on cardiometabolic health
Eugenia Morselli et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
Natriuretic peptides in the control of lipid metabolism and insulin sensitivity
K. Verboven et al.
OBESITY REVIEWS (2017)
Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance
Wei Wu et al.
SCIENCE SIGNALING (2017)
Interplay between Obesity-Induced Inflammation and cGMP Signaling in White Adipose Tissue
Abhishek Sanyal et al.
CELL REPORTS (2017)
Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance
Wei Wu et al.
SCIENCE SIGNALING (2017)
Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction
Masaru Obokata et al.
CIRCULATION (2017)
Attenuated atrial natriuretic peptide-mediated lipolysis in subcutaneous adipocytes of obese type 2 diabetic men
Kenneth Verboven et al.
CLINICAL SCIENCE (2016)
Targeting cardiac natriuretic peptides in the therapy of diabetes and obesity
Cedric Moro
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism
Tom Ashmore et al.
BMC BIOLOGY (2015)
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
Dong I. Lee et al.
NATURE (2015)
Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue
Linda S. Hoffmann et al.
NATURE COMMUNICATIONS (2015)
A Multicenter, Double-Blind, Placebo-Controlled Trial of the PDE9A Inhibitor, PF-04447943, in Alzheimer's Disease
Elias M. Schwam et al.
CURRENT ALZHEIMER RESEARCH (2014)
PDE5 inhibitor efficacy is estrogen dependent in female heart disease
Hideyuki Sasaki et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
A heart-adipose tissue connection in the regulation of energy metabolism
Sheila Collins
NATURE REVIEWS ENDOCRINOLOGY (2014)
Metabolic actions of natriuretic peptides and therapeutic potential in the metabolic syndrome
Nina Schlueter et al.
PHARMACOLOGY & THERAPEUTICS (2014)
Natriuretic peptides and cGMP signaling control of energy homeostasis
Cedric Moro et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Higher Natriuretic Peptide Levels Associate With a Favorable Adipose Tissue Distribution Profile
Ian J. Neeland et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)
Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives
Patrick C. Even et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2012)
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
Marica Bordicchia et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Design and Discovery of 6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of Cognitive Disorders
Patrick R. Verhoest et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK
Sandra C. Souza et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Alterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity
B. Omar et al.
NUTRITION & DIABETES (2011)
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
Shomit Sengupta et al.
NATURE (2010)
Processing of Pro-Brain Natriuretic Peptide Is Suppressed by O-Glycosylation in the Region Close to the Cleavage Site
Alexander G. Semenov et al.
CLINICAL CHEMISTRY (2009)
Inhibition of the actions of peroxisome proliferator-activated receptor a on obesity by estrogen
Sunhyo Jeong et al.
OBESITY (2007)
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38α MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
J Robidoux et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Interaction of oestrogen and peroxisome proliferator-activated receptors with apolipoprotein(a) gene enhancers
LH Puckey et al.
BIOCHEMICAL JOURNAL (2002)