The Rise of Soft Neural Electronics

Neuroscience aims at gaining a better understanding of the mechanism and function of neural systems, but its development is usually limited by the available tools to probe and stimulate the neural system. Advanced electronic devices can receive and send physical/chemical signals from and to biological systems, thus opening opportunities for neuroscience. However, the soft mechanical nature of neural tissue poses challenges for conventional rigid electronics, as the implantation of stiff electronic devices causes a mixture of side effects, including immunoreaction, chronic damage to the surrounding tissue and device dysfunction. The emerging soft electronics offer promises to solve the mechanical mismatch between artificial devices and soft neural tissues. With multiple functions integrated, they are beneficial to complex behavior studies. In this perspective, we summarize the current design principles of soft neural electronics and give an outlook on future possibilities.

Automated summary

Neuroscience relies on advanced electronic devices to understand neural systems, and soft electronics show promise in addressing the mechanical challenges posed by rigid implants, enhancing research capabilities.