Temporal Brain MRI Changes From Extrapontine Myelinolysis to Central Pontine Myelinolysis: A Case Report

We present a case that was initially misdiagnosed as drug-related extrapyramidal side effect. However, after the suspected causative drugs were withdrawn, the patient's condition did not improve. Neuroimaging revealed osmotic demyelination syndrome with a temporal pattern of change from extrapontine myelinolysis to central pontine myelinolysis. Given the limited literature on this rare condition, further research to support clinical diagnosis and treatment is needed.

Automated summary

A case initially misdiagnosed as a drug-related extrapyramidal side effect was later diagnosed as osmotic demyelination syndrome with a temporal pattern of change on neuroimaging. Despite discontinuation of suspected causative drugs, the patient's condition did not improve. Further research is needed to support clinical diagnosis and treatment of this rare condition.