Contributions of photochemistry to bio-based antibacterial polymer materials

Surgical site infections constitute a major health concern that may be addressed by conferring antibacterial properties to surgical tools and medical devices via functional coatings. Bio-sourced polymers are particularly well-suited to prepare such coatings as they are usually safe and can exhibit intrinsic antibacterial properties or serve as hosts for bactericidal agents. The goal of this Review is to highlight the unique contribution of photochemistry as a green and mild methodology for the development of such bio-based antibacterial materials. Photo-generation and photo-activation of bactericidal materials are illustrated. Recent efforts and current challenges to optimize the sustainability of the process, improve the safety of the materials and extend these strategies to 3D biomaterials are also emphasized.

Automated summary

Surgical site infections are a major health concern that can be addressed by imparting antibacterial properties to surgical tools and medical devices. Bio-sourced polymers are well-suited for preparing such coatings, with photochemistry being highlighted as a green and mild methodology for developing bio-based antibacterial materials. Efforts are ongoing to optimize sustainability, improve safety, and extend strategies to 3D biomaterials.