Selective electrochemical para-thiocyanation of aromatic amines under metal-, oxidant- and exogenous-electrolyte-free conditions

An electrochemical oxidative para-C-H-thiocyanation of aromatic amines has been developed to construct thiocyanato aromatic compounds under metal-, oxidant-, and exogenous-electrolyte-free conditions in an undivided cell. The transformation is compatible with a range of primary, secondary, and tertiary amines and shows good functional group tolerance. This approach provides an economical and environmentally benign way for para-thiocyanation of aromatic amines.

Automated summary

An electrochemical oxidative para-C-H-thiocyanation method has been developed for the construction of thiocyanato aromatic compounds from aromatic amines, under metal-free, oxidant-free, and exogenous-electrolyte-free conditions in an undivided cell. This approach is compatible with various types of amines and exhibits good functional group tolerance, providing an economical and environmentally friendly route for the para-thiocyanation of aromatic amines.