4.5 Article

Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Therapeutic targeting of RAS: New hope for drugging the undruggable

Imran Khan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2020)

Article Biochemistry & Molecular Biology

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids

Svenja Wiechmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf

Ziyang Zhang et al.

ACS CENTRAL SCIENCE (2020)

Article Biochemistry & Molecular Biology

Structural and functional characterization of fast-cycling RhoF GTPase

Ryota Sugawara et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Drugging an undruggable pocket on KRAS

Dirk Kessler et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes et al.

Review Pharmacology & Pharmacy

Cell-Penetrating Peptides: From Basic Research to Clinics

Giulia Guidotti et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2017)

Article Biochemistry & Molecular Biology

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew E. Welsch et al.

Article Biochemistry & Molecular Biology

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Andrew S. Dixon et al.

ACS CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

Sai Krishna Athuluri-Divakar et al.

Article Biochemistry & Molecular Biology

Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit

Daniel A. Ritt et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides

James E. Dixon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Biochemistry & Molecular Biology

Quantitative assessment of cellular uptake and cytosolic access of antibody in living cells by an enhanced split GFP complementation assay

Ji-sun Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

Integrated RAS signaling defined by parallel NMR detection of effectors and regulators

Matthew J. Smith et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Multidisciplinary Sciences

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Cosimo Commisso et al.

NATURE (2013)

Article Multidisciplinary Sciences

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction

Fumi Shima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

High-resolution multi-dimensional NMR spectroscopy of proteins in human cells

Kohsuke Inomata et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes

A Fujioka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemical Research Methods

Cell-penetrating peptides:: A comparative membrane toxicity study

K Saar et al.

ANALYTICAL BIOCHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Recognizing and defining true Ras binding domains 1:: Biochemical analysis

S Wohlgemuth et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex

C Kiel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biotechnology & Applied Microbiology

Cell surface adherence and endocytosis of protein transduction domains

M Lundberg et al.

MOLECULAR THERAPY (2003)