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Cytokine Storm
David C. Fajgenbaum et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Tocilizumab for Covid-19-The Ongoing Search for Effective Therapies
Edmund Huang et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Blockage of interleukin-1β with canakinumab in patients with Covid-19
Lorenza Landi et al.
SCIENTIFIC REPORTS (2020)
Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study
Brandon J. Webb et al.
LANCET RHEUMATOLOGY (2020)
SARS-CoV-2-specific T cell responses and correlations with COVID-19 patient predisposition
Arne Sattler et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome
Alessandra Sacchi et al.
CELL DEATH & DISEASE (2020)
Pathology and Pathogenesis of SARS-CoV-2 Associated with Fatal Coronavirus Disease, United States
Roosecelis B. Martines et al.
EMERGING INFECTIOUS DISEASES (2020)
Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19
Lucie Rodriguez et al.
CELL REPORTS MEDICINE (2020)
Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study
Giulio Cavalli et al.
LANCET RHEUMATOLOGY (2020)
T cell responses in patients with COVID-19
Zeyu Chen et al.
NATURE REVIEWS IMMUNOLOGY (2020)
COVID-19: immunopathogenesis and Immunotherapeutics
Li Yang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
The trinity of COVID-19: immunity, inflammation and intervention
Matthew Zirui Tay et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study
Li Tan et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Canakinumab in a subgroup of patients with COVID-19
Claudio Ucciferri et al.
LANCET RHEUMATOLOGY (2020)
Emerging Principles in Myelopoiesis at Homeostasis and during Infection and Inflammation
Joachim L. Schultze et al.
IMMUNITY (2019)
Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome
Chelsea Kotch et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2019)
IL-6 and IL-8 secreted by tumour cells impair the function of NK cells via the STAT3 pathway in oesophageal squamous cell carcinoma
Jian Wu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Biological and clinical significance of T helper 17 cell plasticity
Alessio Mazzoni et al.
IMMUNOLOGY (2019)
Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice
Jonna B. Westover et al.
PATHOGENS (2019)
Clinical significance of lymphocytopenia in patients hospitalized with pneumonia caused by influenza virus
Valeria Bellelli et al.
CRITICAL CARE (2019)
Advances in the understanding and treatment of sepsis-induced immunosuppression
Fabienne Venet et al.
NATURE REVIEWS NEPHROLOGY (2018)
Management of Sepsis-Induced Immunosuppression
Fabienne Venet et al.
CRITICAL CARE CLINICS (2018)
A pattern-based approach to reactive lymphadenopathies
Alexandar Tzankov et al.
SEMINARS IN DIAGNOSTIC PATHOLOGY (2018)
Cytokine release syndrome
Alexander Shimabukuro-Vornhagen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Epidemiology and Immune Pathogenesis of Viral Sepsis
Gu-Lung Lin et al.
FRONTIERS IN IMMUNOLOGY (2018)
A Review of Recent Advances Using Tocilizumab in the Treatment of Rheumatic Diseases
Andrea Rubbert-Roth et al.
RHEUMATOLOGY AND THERAPY (2018)
Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections
Antoine Roquilly et al.
IMMUNITY (2017)
Understanding Immunosuppression after Sepsis
Fatemeh Fattahi et al.
IMMUNITY (2017)
Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
Rudragouda Channappanavar et al.
CELL HOST & MICROBE (2016)
Balance between Hyperinflammation and Immunosuppression in Sepsis
Hemang Yadav et al.
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Transient Migration of Large Numbers of CD14++ CD16+ Monocytes to the Draining Lymph Node after Onset of Inflammation
Hege Lund et al.
FRONTIERS IN IMMUNOLOGY (2016)
Inhibition of Natural Killer Cell Cytotoxicity by Interleukin-6: Implications for the Pathogenesis of Macrophage Activation Syndrome
Loredana Cifaldi et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Peripheral CD27-CD21- B-cells represent an exhausted lymphocyte population in hepatitis C cirrhosis
Hiroyoshi Doi et al.
CLINICAL IMMUNOLOGY (2014)
An increased level of IL-6 suppresses NK cell activity in peritoneal fluid of patients with endometriosis via regulation of SHP-2 expression
Young-Ju Kang et al.
HUMAN REPRODUCTION (2014)
Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection
Gaia Sciaranghella et al.
AIDS (2013)
Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections
Micah T. McClain et al.
JOURNAL OF CLINICAL VIROLOGY (2013)
Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach
Richard S. Hotchkiss et al.
LANCET INFECTIOUS DISEASES (2013)
The three human monocyte subsets: implications for health and disease
Kok Loon Wong et al.
IMMUNOLOGIC RESEARCH (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Expansion of a unique CD57+ NKG2Chi natural killer cell subset during acute human cytomegalovirus infection
Sandra Lopez-Verges et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
Richard A. Morgan et al.
MOLECULAR THERAPY (2010)
Diagnostic Importance of Relative Lymphopenia as a Marker of Swine Influenza (H1N1) in Adults
Burke A. Cunha et al.
CLINICAL INFECTIOUS DISEASES (2009)
Myeloid-derived suppressor cells as regulators of the immune system
Dmitry I. Gabrilovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
What caused lymphopenia in SARS and how reliable is the lymphokine status in glucocorticoid-treated patients?
N. S. Panesar
MEDICAL HYPOTHESES (2008)
SARS: Systematic review of treatment effects
Lauren J. Stockman et al.
PLOS MEDICINE (2006)
Effects of severe acute respiratory syndrome (SARS) coronavirus infection on peripheral blood lymphocytes and their subsets
ZP He et al.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2005)
Extrafollicular proliferation of B cells in the absence of follicular hyperplasia:: a distinct reaction pattern in lymph nodes correlated with primary or recall type responses
A Brighenti et al.
HISTOPATHOLOGY (2005)
Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome
CK Wong et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2004)
Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
N Lee et al.
JOURNAL OF CLINICAL VIROLOGY (2004)
A major outbreak of severe acute respiratory syndrome in Hong Kong
N Lee et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals
S Moir et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)