期刊
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 25, 期 12, 页码 11181-11191出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11356-017-8400-3
关键词
Gold nanoparticles; Trophic transfer; Periphytic biofilm; Gammarus fossarum; Gene transcription; Digestive enzyme activity; Mitochondrial disruption
资金
- Agence Nationale de Securite Sanitaire de l'Alimentation, de l'Environnement et du Travail (ANSES) research program TRONANO
- Agence Nationale de la Recherche (ANR) in the CITTOXIC-Nano program [ANR-14-CE21-0001-01]
- Investments for the future Program within the Cluster of Excellence COTE [ANR-10-LABX-45]
- Agence Nationale de la Recherche (ANR) [ANR-14-CE21-0001] Funding Source: Agence Nationale de la Recherche (ANR)
This work addressed the trophic transfer and effects of functionalized gold nanoparticles (AuNPs) from periphytic biofilms to the crustacean Gammarus fossarum. Biofilms were exposed for 48 h to 10 nm positively charged functionalized AuNPs at two concentrations, 4.6 and 46 mg/L, and crustaceans G. fossarum grazed on these for 7 days, with daily biofilm renewal. Gold bioaccumulation in biofilm and crustacean were measured to estimate the trophic transfer ratio of these AuNP, and, for the first time, a transcriptomic approach and transmission electron microscopy observations in the crustacean were made. These two approaches showed cellular damage caused by oxidative stress and, in particular, an impact of these AuNPs on mitochondrial respiration. Modulation of digestive enzyme activity was also observed, suggesting modifications of digestive functions. The damage due to these nanoparticles could then have vital consequences for the organisms during chronic exposure.
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