期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 131, 期 23, 页码 -出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI154983
关键词
-
资金
- NIH [R01EY023336]
The study successfully implanted an electrode array with 96 penetrating electrodes in the visual cortex of a blind patient, allowing the patient to perceive visual patterns created by passing current through array electrodes. Penetrating electrodes require less current to create a visual percept compared to electrodes resting on the cortical surface, but patterned electrical stimulation often fails to produce the expected percept, necessitating further research to understand the relationship between stimulus and perception.
In this issue of the JCI, the dream of restoring useful vision to blind individuals with neurotechnology moves one step closer to realization. Fernandez et al. implanted an electrode array with 96 penetrating electrodes in the visual cortex of a blind patient who had been without light perception for 16 years due to optic neuropathy. Remarkably, the patient was able to perceive visual patterns created by passing current through array electrodes. The use of a penetrating electrode array meant that action potentials from single neurons could be recorded to study the neural response to stimulation. Compared with electrodes resting on the cortical surface, penetrating electrodes require one-tenth the current to create a visual percept. However, patterned electrical stimulation often fails to produce the expected percept for penetrating and surface electrode arrays, highlighting the need for further research to untangle the relationship between stimulus and perception.
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