4.5 Article

Genomic Insight into the Antimicrobial Resistance of Streptococcus Suis - Six Countries, 2011-2019

期刊

CHINA CDC WEEKLY
卷 3, 期 47, 页码 994-998

出版社

Chinese Center for Disease Control and Prevention
DOI: 10.46234/ccdcw2021.242

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资金

  1. National Key Research and Development Program of China [2017YFC 1601501, 2016YFD0501305]
  2. Key Research and Development Program of Shandong Province [2019JZZY010719]

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The study found that the prevalence of antimicrobial resistance genes in pig isolates of S. suis was higher than in human isolates, and the prevalence of these genes also varied with serotype. These data will help guide rational drug use in the clinic to better protect the health of humans and animals.
What is already known on this topic? Streptococcus suis (S. suis) is a zoonotic pathogen causing disease in humans and animals, and the emergence of its increased resistance to antimicrobial agents has become a significant challenge in many countries. What is added by this report? Using whole genome sequencing data to accurately predict antimicrobial resistance determinants, it was found that the prevalence of antimicrobial resistance genes was higher in the pig isolates of S. suis than in the human isolates and that the prevalence of these genes varied with serotype. What are the implications for public health practice? The data regarding S. suis antimicrobial resistance will help guide rational drug use in the clinic to better protect the health of humans and animals.y

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