相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Studies on the mechanism of general anesthesia
Mahmud Arif Pavel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
A lower X-gate in TASK channels traps inhibitors within the vestibule
Karin E. J. Rodstrom et al.
NATURE (2020)
Sodium ions allosterically modulate the M2 muscarinic receptor
Sheli Friedman et al.
SCIENTIFIC REPORTS (2020)
Structural basis for pH gating of the two-pore domain K+channel TASK2
Baobin Li et al.
NATURE (2020)
Polynuclear Ruthenium Amines Inhibit K2P Channels via a Finger in the Dam Mechanism
Lianne Pope et al.
CELL CHEMICAL BIOLOGY (2020)
eeFit: a Microsoft Excel-embedded program for interactive analysis and fitting of experimental dose-response data
Michel Vivaudou
BIOTECHNIQUES (2019)
Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes
Shoji Maeda et al.
SCIENCE (2019)
The Structural Basis for the Binding of Repaglinide to the Pancreatic KATP Channel
Dian Ding et al.
CELL REPORTS (2019)
Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
Gregory M. Martin et al.
ELIFE (2019)
Two-pore domain potassium channels: emerging targets for novel analgesic drugs: IUPHAR Review 26
Kirin Gada et al.
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Domain insertion permissibility-guided engineering of allostery in ion channels
Willow Coyote-Maestas et al.
NATURE COMMUNICATIONS (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors
Michael Schoenrock et al.
COMMUNICATIONS BIOLOGY (2019)
Exploring the Viral Channel KcvPBCV-1 Function via Computation
Alma E. V. Andersson et al.
JOURNAL OF MEMBRANE BIOLOGY (2018)
Protein and Chemical Determinants of BL-1249 Action and Selectivity for K2P Channels
Lianne Pope et al.
ACS CHEMICAL NEUROSCIENCE (2018)
Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels
Ismail Ben Soussia et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
A light-gated potassium channel for sustained neuronal inhibition
Laura Alberio et al.
NATURE METHODS (2018)
K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site
Marco Lolicato et al.
NATURE (2017)
Tuning the allosteric regulation of artificial muscarinic and dopaminergic ligand-gated potassium channels by protein engineering of G protein-coupled receptors
Christophe J. Moreau et al.
Scientific Reports (2017)
Molecular structure of human KATP in complex with ATP and ADP
Kenneth Pak Kin Lee et al.
ELIFE (2017)
Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
Gregory M. Martin et al.
ELIFE (2017)
Functional mapping of the N-terminal arginine cluster and C-terminal acidic residues of Kir6.2 hannel fused to a G protein-coupled receptor
Maria A. Principalli et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)
Sodium permeable and hypersensitive TREK-1 channels cause ventricular tachycardia
Niels Decher et al.
EMBO MOLECULAR MEDICINE (2017)
Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
Jean-Pierre Changeux et al.
CELL (2016)
Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels
Joshua Levitz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties
Sandy Blin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel
Xuan-Yu Meng et al.
SCIENTIFIC REPORTS (2016)
Ion-Channel-Coupled Receptor-Based Platform for a Real-Time Measurement of G-Protein-Coupled Receptor Activities
Jong Hyun Lim et al.
ACS NANO (2015)
Tectonics of a K+ channel: The importance of the N-terminus for channel gating
F. Hoffgaard et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Ion Channel Engineering: Perspectives and Strategies
Prakash Subramanyam et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
Engineering of a light-gated potassium channel
Cristian Cosentino et al.
SCIENCE (2015)
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac
Yin Yao Dong et al.
SCIENCE (2015)
Engineering a Ca++-Sensitive (Bio) Sensor from the Pore-Module of a Potassium Channel
Mattia Lorenzo DiFrancesco et al.
SENSORS (2015)
G Protein-Coupled Receptor Signaling to Kir Channels in Xenopus Oocytes
Candice Hatcher-Solis et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2014)
Physical mechanism for gating and mechano sensitivity of the human TRAAK K+ channel
Stephen G. Brohawn et al.
NATURE (2014)
Functional Assay for T4 Lysozyme-Engineered G Protein-Coupled Receptors with an Ion Channel Reporter
Katarzyna Niescierowicz et al.
STRUCTURE (2014)
The voltage-sensing domain of a phosphatase gates the pore of a potassium channel
Cristina Arrigoni et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
A virus-encoded potassium ion channel is a structural protein in the chlorovirus Paramecium bursaria chlorella virus 1 virion
Giulia Romani et al.
JOURNAL OF GENERAL VIROLOGY (2013)
Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel
Stephen G. Brohawn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Engineering of an Artificial Light-Modulated Potassium Channel
Lydia N. Caro et al.
PLOS ONE (2012)
Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel
Stephen G. Brohawn et al.
SCIENCE (2012)
Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1
Alexandria N. Miller et al.
SCIENCE (2012)
Molecular regulations governing TREK and TRAAK channel functions
Jacques Noel et al.
CHANNELS (2011)
β2-Adrenergic Ion-Channel Coupled Receptors as Conformational Motion Detectors
Lydia N. Caro et al.
PLOS ONE (2011)
Artificial Modulation of the Gating Behavior of a K+ Channel in a KvAP-DNA Chimera
Andrew Wang et al.
PLOS ONE (2011)
Molecular Background of Leak K+ Currents: Two-Pore Domain Potassium Channels
Peter Enyedi et al.
PHYSIOLOGICAL REVIEWS (2010)
Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design
Jean Mazella et al.
PLOS BIOLOGY (2010)
Control of the single channel conductance of K2P10.1 (TREK-2) by the amino-terminus: role of alternative translation initiation
Dina Simkin et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
MGlu4 potentiation of K(2P)2.1 is dependant on C-terminal dephosphorylation
Stuart M. Cain et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Coupling ion channels to receptors for biomolecule sensing
Christophe J. Moreau et al.
NATURE NANOTECHNOLOGY (2008)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera
Motohiko Nishida et al.
EMBO JOURNAL (2007)
Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels
J Murbartián et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Construction of a cyclic nucleotide-gated KcsA K+ channel
UM Ohndorf et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
The viral potassium channel Kcv: structural and functional features
S Gazzarrini et al.
FEBS LETTERS (2003)
Voltage-dependence of virus-encoded miniature K+ channel Kcv
S Gazzarrini et al.
JOURNAL OF MEMBRANE BIOLOGY (2002)
Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes
T Jespersen et al.
BIOTECHNIQUES (2002)
Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors
F Lesage et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A potassium channel protein encoded by chlorella virus PBCV-1
B Plugge et al.
SCIENCE (2000)