期刊
JOURNAL OF COMPUTER CHEMISTRY-JAPAN
卷 20, 期 3, 页码 97-99出版社
SOC COMPUTER CHEMISTRY, JAPAN
DOI: 10.2477/jccj.2021-0045
关键词
Hemoglobin; Allostery regulation; Chloride ion; Bridging hydrogen bond; Time-series clustering method
The investigation found that bridging hydrogen bonds via Cl- do not significantly contribute to the structural regulation of human adult hemoglobin.
In this letter, we investigated the contribution of bridging hydrogen bonds (BHB) via Cl- on the T-R transition of human adult hemoglobin (HbA). We applied the time-series clustering method to time-series data of the alpha beta dimer rotation angle phi and the total number of the BHBs. Compared with the above two results, we have concluded that Cl- BHBs do not significantly contribute to the structural regulation of HbA.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据