期刊
ENVIRONMENTAL SCIENCE & TECHNOLOGY
卷 51, 期 22, 页码 13061-13069出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.est.7b03623
关键词
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资金
- U.S. National Science Foundation (NSF) Award [OISE:1545756]
- Overseas Environmental Antibiotic Resistance Surveillance - OVERSEAS, FLAD/NSF - Research Networks Program Portugal/EUA - Environmental Science [2015/298]
- Swiss National Research Programme Antimicrobial Resistance (NRP 72) Project [407240_167116]
- Swiss National Science Foundation (SNF) [407240_167116] Funding Source: Swiss National Science Foundation (SNF)
- Office Of Internatl Science &Engineering
- Office Of The Director [1545756] Funding Source: National Science Foundation
Antibiotic resistance is a pervasive global health threat. To combat the spread of resistance, it is necessary to consider all possible sources and understand the pathways and mechanisms by which resistance disseminates. Best management practices are urgently needed to provide barriers to the spread of resistance and maximize the lifespan of antibiotics as a precious resource. Herein we advise upon the need for coordinated national and international strategies, highlighting three essential components: (1) Monitoring, (2) Risk Assessment, and (3) Mitigation of antibiotic resistance. Central to all three components is What exactly to monitor, assess, and mitigate? We address this question within an environmental framework, drawing from fundamental microbial ecological processes driving the spread of resistance.
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