期刊
EMERGING INFECTIOUS DISEASES
卷 27, 期 12, 页码 3173-3175出版社
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2712.211621
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资金
- Health and Medical Research Fund [HMRF COVID-190115]
- Commissioned Research on Control of Infectious Diseases (phase III) from the Health and Medical Research Fund
- Commissioned Research on Control of Infectious Diseases (phase IV) from the Health and Medical Research Fund
The infectivity of SARS-CoV-2 in deceased hosts and organisms is still unclear. A study on transgenic K18 hACE2 mice showed that virus infectivity in the lungs decreased by over 96% five days after host death, along with a 48.2% decrease in RNA copies.
The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after host death. Five days after death, virus infectivity in the lung declined by >96% and RNA copies declined by 48.2%.
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