期刊
ENDOCRINE JOURNAL
卷 -, 期 -, 页码 -出版社
JAPAN ENDOCRINE SOC
DOI: 10.1507/endocrj.EJ21-0408
关键词
Type 1 diabetes mellitus; Quality of life; Sleep quality
资金
- Ministry of Health, Labor and Welfare, Health and Labor Sciences Research Grants, Japan [17K09841]
- Grants-in-Aid for Scientific Research [17K09841] Funding Source: KAKEN
This study reveals the relationship between quality of life and sleep quality in patients with type 1 diabetes mellitus, indicating that assessing and managing sleep quality may be necessary to improve QOL for diabetes patients. The study also found differences in the relationship between QOL and PSQI subscales in type 1 diabetes mellitus patients compared to type 2 diabetes mellitus patients.
This study aimed to reveal the relationship between quality of life (QOL) and sleep quality in patients with type 1 diabetes mellitus (T1DM). Overall, 202 patients with T1DM were registered in our study, and 192 were eligible for analysis. Baseline characteristics and laboratory values were determined. Patients completed the Japanese versions of the Pittsburgh Sleep Quality Index (PSQI) and Diabetes Therapy-Related QOL (DTR-QOL) questionnaires. We investigated the relationship between the global PSQI and DTR-QOL total scores by using linear regression analysis. In univariate regression analysis, DTR-QOL total scores were associated with body mass index, alcohol consumption, hypertension, hemoglobin A1c (HbA1c), and global PSQI score (all p-value <0.05) but not with sleep duration. When the association between PSQI subscales and DTR-QOL total scores was examined, DTR-QOL total scores were significantly related to subjective sleep quality and daytime dysfunction. In a multivariate regression analysis, the global PSQI score was negatively related to DTR-QOL total scores. Patients with an HbA1c concentration >= 8.0% had significantly lower DTR-QOL total scores. We revealed a relationship between QOL and sleep quality in T1DM patients and showed that the relationship between QOL and PSQI subscales in T1DM patients may be different from that in patients with type 2 diabetes mellitus. Assessing and managing sleep quality may be necessary for patients with diabetes to improve QOL.
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