Chemical compositions of Sideritis albiflora Hub. - Mor.

Background and Aims: Sideritis species (Lamiaceae) which are quite widespread in the Mediterranean region and represented by 46 species and 53 taxa in Turkey, are often used as a antirheumatic, anti-inflammatory, antimicrobial and diuretic remedies. Methods: In this study, the infusion (INF), essential oil (E0) and methanolic extract (ME) of chemical compounds prepared from aerial parts of Sideritis albiflora Hub.-Mor. (endemic) were investigated. Results: The presence of chlorogenic acid, verbascoside, forsythoside, apigenin glucoside, and isoscutellarein derivatives in the infusion and methanol extract of the plant was determined by LC-MS / MS analysis. In addition, the main constituents of the essential oil were found as germacrene D (23.5%), beta-caryophyllene (13.6%) and caryophylene oxide (8.0%) by GC / MS and GC / FID simultaneously. Conclusion: In this study, the essential oil, the methanolic extract and the infusion of S. albiflora species were prepared and their chemical compositions elucidated. It was determined that the essential oil chemical compound composition is rich in terms of the sesquiterpene group. Infusions of aerial parts of some Sideritis species have traditionally been used in the treatment of many diseases. Accordingly, the fact that the phenolic compounds of S. albiflora infusion have not been studied before increases the importance of this study. In addition, the therapeutic effect was shown to be related to major S. albiflora compounds, and the correlation between in vitro activity and ethnobotanical use was evaluated. The effective phenolic compounds contained in S. albiflora are thought to support the traditional uses of the plant.

Automated summary

This study investigated the chemical components of Sideritis albiflora, a plant species endemic to Turkey, revealing the presence of various compounds such as chlorogenic acid and verbascoside in the infusion and methanol extract, and germacrene D and beta-caryophyllene in the essential oil. Traditionally, infusions of some Sideritis species have been used to treat various diseases, and the lack of research on phenolic compounds in S. albiflora infusions highlights the importance of this study. The effective phenolic compounds in S. albiflora are believed to support the plant's traditional uses.