Digital Laser Doppler Flowmetry: Device, Signal Processing Technique, and Clinical Testing

A method and a device for digital laser Doppler flowmetry are proposed. An approach to signal processing based on analysis of the power spectrum amplitude distribution over Doppler broadening frequencies is suggested. A prototype of the device is presented; its technical characteristics and settings used in tests are described. The method was tested in healthy volunteers of different ages and patients with type 2 diabetes mellitus. The research led to the development of binary classifiers for classifying volunteers and patients into groups according to the functional state of microcirculation.

Automated summary

A method and device for digital laser Doppler flowmetry were proposed, with signal processing based on analysis of power spectrum amplitude distribution over Doppler broadening frequencies. The research led to the development of binary classifiers for classifying volunteers and patients based on microcirculation functional state.