期刊
ENVIRONMENT INTERNATIONAL
卷 106, 期 -, 页码 257-266出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2017.06.001
关键词
Heart failure; Elderly; Climate changes; Fine particulate matter; Lag effect; Canada
资金
- Green Fund, action plan of on climate changes of the government of Quebec, Canada
Background: There are limited data on the effects of climate and air pollutant exposure on heart failure (HF) within taking into account individual and contextual variables. Objectives: We measured the lag effects of temperature, relative humidity, atmospheric pressure and fine particulate matter (PM2.5) on hospitalizations and deaths for HF in elderly diagnosed with this disease on a 10-year period in the province of Quebec, Canada. Methods: Our population-based cohort study included 112,793 elderly diagnosed with HF between 2001 and 2011. Time dependent Cox regression models approximated with pooled logistic regressions were used to evaluate the 3-and 7-day lag effects of daily temperature, relative humidity, atmospheric pressure and PM2.5 exposure on HF morbidity and mortality controlling for several individual and contextual covariates. Results: Overall, 18,309 elderly were hospitalized and 4297 died for the main cause of HF. We observed an increased risk of hospitalizations and deaths for HF with a decrease in the average temperature of the 3 and 7 days before the event. An increase in atmospheric pressure in the previous 7 days was also associated with a higher risk of having a HF negative outcome, but no effect was observed in the 3-day lag model. No association was found with relative humidity and with PM2.5 regardless of the lag period. Conclusions: Lag effects of temperature and other meteorological parameters on HF events were limited but present. Nonetheless, preventive measures should be issued for elderly diagnosed with HF considering the burden and the expensive costs associated with the management of this disease.
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