期刊
ACTA CHIMICA SLOVENICA
卷 68, 期 4, 页码 753-764出版社
SLOVENSKO KEMIJSKO DRUSTVO
DOI: 10.17344/acsi.2021.7198
关键词
Electroporation; cell membrane; electrochemotherapy; gene electrotransfer; tissue ablation; nanotechnology
资金
- Slovenian Research Agency [P1-0207, P2-0249]
Electroporation increases cell membrane permeability through high-voltage electric pulses and is widely used in medicine. It helps the entry or exit of hydrophilic molecules but also poses challenges in research and application.
Electroporation is used to increase the permeability of the cell membrane through high-voltage electric pulses. Nowadays, it is widely used in different areas, such as medicine, biotechnology, and the food industry. Electroporation induces the formation of hydrophilic pores in the lipid bilayer of cell membranes, to allow the entry or exit of molecules that cannot otherwise cross this hydrophobic barrier. In this article, we critically review the basic principles of electroporation, along with the advantages and drawbacks of this method. We discuss the effects of electroporation on the key components of biological membranes, as well as the main applications of this procedure in medicine, such as electrochemotherapy, gene electrotransfer, and tissue ablation. Finally, we define the most relevant challenges of this promising area of research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据