4.2 Article

Effect of Sufentanil Preemptive Analgesia on Anesthesia Recovery Period of Patients undergoing Thoracoscopic Surgery and Nursing Observation

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INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
卷 83, 期 -, 页码 226-230

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INDIAN PHARMACEUTICAL ASSOC
DOI: 10.36468/pharmaceutical-sciences.spl.398

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Sufentanil; preemptive analgesia; thoracoscopy; hypertension

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The study found that intravenous injection of sufentanil before general anesthesia in patients undergoing thoracoscopic surgery can significantly reduce postoperative pain. In addition, sufentanil is considered as a potential preemptive analgesic drug, which may be used to manage postoperative pain in short-term surgeries.
We aim to investigate the effectiveness of intravenous injection of sufentanil before the induction of general anesthesia in patients undergoing thoracoscopic surgery to control pain in the postoperative recovery period and analyze its impact on the qualified rate of nursing and the occurrence of nursing adverse events. Selected 146 patients who underwent thoracoscopic surgery in our department from February 2018 to May 2020. 73 patients with intraoperative intravenous injection of sufentanil were selected as the experimental group and 73 patients with intraoperative intravenous injection of normal saline were selected as the control group. Compared both groups with visual analogue scales scores and Bruggrmann comfort scale scores at 30 min, 1 h, 2 h and 3 h after operation. At the same time, compared both groups with heart rate, blood oxygen saturation, mean arterial pressure and bispectral index values during the anesthesia recovery period and extubation and after extubation and qualified rate of nursing and its nursing adverse events. The heart rate, mean arterial pressure and bispectral index values of the two groups of patients at the time of extubation and 5 min after extubation were significantly different (p<0.05). Visual analogue scale scores and Bruggrmann comfort scale scores of both groups at 30 min, 1 h, 2 h and 3 h after surgery had significant differences (p<0.05). It had significant differences of both groups in the qualified rate of nursing and its adverse events (p<0.05), which were statistically significant. For patients undergoing thoracoscopic surgery, intravenous injection of sufentanil before general anesthesia can promote better postoperative pain. Sufentanil is considered as a potential auxiliary drug for preemptive analgesia, which is used to manage postoperative pain in short-term surgery and is worthy of clinical promotion.

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