期刊
ANALYTICAL AND QUANTITATIVE CYTOPATHOLOGY AND HISTOPATHOLOGY
卷 43, 期 6, 页码 553-559出版社
SCI PRINTERS & PUBL INC
关键词
apoptosis; pregnancy; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand
类别
资金
- Jingzhou Science and Technology Development Plan [2015AC45, 2016AE51-2]
- Hubei Province Health and Family Planning Scientific Research Project [WJ2017Z024, WJ2018H175, WJ2019M085, WJ2019F126, WJ2018H199]
- Hubei Provincial Natural Science Foundation of China [2018CFB775]
- Hubei Clinical Medicine Research Center for Individualized Cancer Diagnosis and Therapy
TRAIL receptor is widely expressed in the decidual interface and plays a crucial role in regulating cell function and inducing inflammatory cell differentiation in early pregnancy. Abnormal expression of TRAIL receptor can lead to early abortion and other pregnancy complications.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is widely expressed in decidual interface, and TRAIL receptor specifically binds to it and plays a role in cell function regulation. TRAIL receptor is differ-entially expressed in cells such as decidual cells, tro-phoblast cells, and immune cells, which can regulate cytokine secretion, cell proliferation and apoptosis, func-tion shaping, and induce inflammatory cell differentia-tion. Abnormal expression of TRAIL receptor leads to early abortion and other pregnancy complications, which plays an important role in the early pregnancy of hu-mans. This review describes the expression of TRAIL receptor in early pregnancy and provides a new clinical approach to improve the treatment of early pregnancy complications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据