One year in review 2021: systemic sclerosis

Systemic sclerosis is a rare and chronic connective tissue disease with a multifaceted pathogenesis characterised by heterogeneous multi-organ clinical manifestations. Every year, many studies contribute to enrich the knowledge on the pathogenesis, organ involvement and treatment of this complex and severe disease. We herein provide an overview on the most relevant contributions published in the literature in 2020.

Automated summary

Systemic sclerosis is a rare and chronic connective tissue disease with complex multi-organ clinical manifestations. Studies in 2020 have made significant contributions to enrich the understanding of the pathogenesis, organ involvement, and treatment of this severe disease.