期刊
CURRENT RESEARCH IN BIOTECHNOLOGY
卷 3, 期 -, 页码 1-5出版社
ELSEVIER
DOI: 10.1016/j.crbiot.2020.12.001
关键词
Staphylococcus aureus; Tetraclinis articulata; Biofilm; Essential oil; Antibacterial activity; Antibiofilm activity
资金
- Hassan II University of Casablanca
- Ministry of Higher Education, Scientific Research
The essential oil of sawdust from root burl wood of T. articulata showed strong antibacterial activity against various strains, including Multidrug-Resistant and Methicillin-Resistant S. aureus strains. It also exhibited a significant inhibitory effect on biofilm formation at sub-lethal concentrations for all strains.
The aim of the present study was to determine the chemical composition, antibacterial and antibiofilm activities of the essential oil of sawdust from root burl wood of T. articulata. Nine strains including 8 clinical isolates from catheters-related infections and one ATCC 25923 were tested. Twenty-seven different compounds were identified by GC-MS in the essential oil of T. articulata extracted by hydrodistillation. Carvacrol and cedrol were the principal compounds representing 34.37 +/- 0.07 and 11.07 +/- 0.09 respectively. The EO had a strong antibacterial activity against all strains including one Multidrug-Resistant (MDR) and two Methicillin-Resistant S. aureus strains. Inhibition Zone Diameter (IZD) values ranged from 25 to 44 mm and the MIC values, determinated by microdilution method, ranged from 0.19 to 48 nL/mL. The EO had bactericidal effect and also exhibited at sub-lethal concentrations a very important inhibitory effect of biofilm formation of all strains.
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