期刊
NATURAL PRODUCT RESEARCH
卷 36, 期 4, 页码 989-993出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1839450
关键词
GC-MS; oxygenated monoterpenes; 18-cineole; Staphylococcus aureus; Streptococcus faecalis; MIC
This study investigated the chemical composition and in vitro antibacterial effect of Laurus nobilis leaves essential oil grown in North West Algerian conditions. The results showed that the essential oil had a high content of oxygenated monoterpenes and exhibited significant antibacterial activity against Streptococcus faecalis and Staphylococcus aureus.
Chemical composition determination and in vitro antibacterial effect of Essential Oil (EO) of Laurus nobilis leaves grown North West Algerian conditions were investigated. Antibacterial activity was evaluated by the technique of the paper disc diffusion. Extractions were carried out with Clevenger apparatus and EO compositions were investigated by gas chromatography coupled to mass spectrometry (GC-MS) analysis. The oxygenated monoterpenes (MO) were the class with the highest contents, represent 59% of the EO. A total of twenty-seven of these compounds were identified, the major components were 1,8-cineole (30.1%), alpha-terpynil acetate (21.6%), methyl eugenol (16.9%) of the total oil. The highest antibacterial power of the EO tested was recorded in Streptococcus faecalis and Staphylococcus aureus with the zone diameter of inhibition 13.6 and 11.2 mm respectively and a minimal inhibitory concentration (MIC) of 0.25 mg/mL for both these two strains.
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