期刊
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
卷 71, 期 5, 页码 359-375出版社
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2020.1838518
关键词
Biomaterials; chronic wounds; hydrogels; nanotechnology; patents; scaffolds; wound healing
This review article discusses the pathophysiology of chronic wounds, current treatment approaches, and potential biomaterials used for wound healing. The focus is on biopolymers that utilize nanotechnology to enhance skin regeneration in chronic wounds.
Chronic, non-healing diabetic wounds put a massive economic burden on health services causing patient incompliance and discomfort. Thorough interpreting of chronic wound pathophysiology led to the fabrication of targeted systems of drug delivery that can improve and accelerate the wound healing process. Natural polymers or biopolymers are now explored for the fabrication of wound dressings. Hence, in this review article, the pathophysiological aspects of chronic wounds, current treatment approaches, and potential biomaterials employed for treating wounds are explicated. The main emphasis is on biopolymers which aid in creating innovative systems based on nanotechnology for effective skin generation in chronic wounds.
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