期刊
OPEN FORUM INFECTIOUS DISEASES
卷 3, 期 3, 页码 -出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofw165
关键词
coronavirus infections; disease outbreaks; infectious disease transmission; Middle East respiratory syndrome coronavirus; Saudi Arabia
资金
- Saudi Arabia Ministry of Health and the United States Centers for Disease Control and Prevention as part of an urgent public health response
During July-August 2015, the number of cases of Middle East respiratory syndrome (MERS) reported from Saudi Arabia increased dramatically. We reviewed the 143 confirmed cases from this period and classified each based upon likely transmission source. We found that the surge in cases resulted predominantly (90%) from secondary transmission largely attributable to an outbreak at a single healthcare facility in Riyadh. Genome sequencing of MERS coronavirus from 6 cases demonstrated continued circulation of the recently described recombinant virus. A single unique frameshift deletion in open reading frame 5 was detected in the viral sequence from 1 case.
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